316828-01-0Relevant articles and documents
Total synthesis of (-)-reveromycin A
El Sous, Mariana,Ganame, Danny,Tregloan, Peter A.,Rizzacasa, Mark A.
, p. 3001 - 3004 (2004)
(Equation Presented) The asymmetric total synthesis of (-)-reveromycin A is described. The key steps involved a Lewis acid catalyzed inverse electron demand hetero-Diels-Alder reaction followed by hydroboration/oxidation to afford the spiroketal core 4 in
Hetero-Diels-Alder synthesis of the spiroketal fragment of reveromycin A
El Sous,Rizzacasa
, p. 8591 - 8594 (2007/10/03)
The asymmetric synthesis of the 6,6-spiroketal fragment 15 of the epidermal growth factor inhibitor reveromycin A (1) is described. A hetero-Diels-Alder reaction was utilized to construct the 6,6-spiroketal 14 and subsequent stereoselective hydroboration