3169-71-9

Usage

Uses

Used in Pharmaceutical Chemistry:
2-(4-Fluorophenoxy)aniline is used as a synthetic precursor for the development of various pharmaceutical compounds. Its unique chemical properties make it a valuable component in the synthesis of potential therapeutic agents, contributing to the creation of new medicines.
Used in Organic Synthesis:
In the field of organic chemistry, 2-(4-Fluorophenoxy)aniline is employed as a building block for the assembly of more complex molecules. Its reactivity and compatibility with other chemical substances facilitate its use in the synthesis of a wide array of organic compounds, expanding the scope of chemical research and development.
Used in Laboratory Research:
2-(4-Fluorophenoxy)aniline is utilized in academic and research settings as a key component in various chemical experiments and studies. Its presence in the synthesis of new compounds aids in advancing the understanding of chemical reactions and the properties of novel molecules.
Used in Industrial Applications:
2-(4-FLUOROPHENOXY)ANILINE is also used in industrial processes, where it serves as a starting material for the production of specialty chemicals and materials. Its role in the synthesis of complex molecules is crucial for the development of innovative products in various industries.

InChI:InChI=1/C12H10FNO/c13-9-5-7-10(8-6-9)15-12-4-2-1-3-11(12)14/h1-8H,14H2

Upstream product

• 371-41-5 4-Fluorophenol 
• 88-73-3 2-Chloronitrobenzene 
• 1493-27-2 ortho-nitrofluorobenzene 
• 4475-59-6 1-(4-fluorophenoxy)-2-nitrobenzene 

Downstream Products

• 1316273-86-5 N-[2-(4-fluorophenoxy)phenyl]acetamide 
• 203303-06-4 1-(4-fluorophenoxy)-2-iodobenzene 
• 76838-21-6 1-Benzoyl-3-[2-(4-fluoro-phenoxy)-phenyl]-thiourea 
• 76840-96-5 [2-(4-Fluoro-phenoxy)-phenyl]-imidazolidin-2-ylidene-amine 
• 76839-02-6 [2-(4-Fluoro-phenoxy)-phenyl]-thiourea 

Relevant academic research and scientific papers

Pyrazinamide compounds, preparation method and application thereof as well as bactericide

The invention relates to the field of pesticide bactericides and discloses pyrazinamide compounds, a preparation method and an application thereof as well as a bactericide. The compounds have the structure shown in formula (I). The pyrazinamide compounds with the novel structure are designed by introducing pyrazine ring fragments in Pyradiflumid and diphenyl ether fragments with wide bioactivity,and the pyrazinamide compounds can be used as novel SDHIs (succinate dehydrogenase inhibitors) or bactericides.

NOVEL TRIAZINE COMPOUND, AND ORGANIC ELECTRONIC ELEMENT AND PLANT-GROWING LIGHTING THAT USE THE SAME

PROBLEM TO BE SOLVED: To provide a triazine compound which has a high triplet energy level and excellent heat resistance, and can be used as an organic electronic element material realizing an element with high efficiency, low voltage and a long life. SOLUTION: In the triazine compound, as represented by the general formula [1] in the figure, a triazine backbone moiety is linked to a dibenzofuran or dibenzothiophene backbone moiety via a biphenyl backbone moiety, where X is an oxygen atom or sulfur atom. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPO&INPIT

Design, synthesis and antifungal activity of novel furancarboxamide derivatives

Twenty-seven novel furancarboxamide derivatives with a diphenyl ether moiety were synthesized and evaluated for their antifungal activity against Rhizoctonia solani, Botrytis cirerea, Valsa Mali and Sphaceloma ampelimum. Antifungal bioassay results indicated that most compounds had good or excellent fungicidal activities for R. solani and S. ampelimum at 20 mg L-1. Among synthesized compounds, compound 18e showed a greater inhibitory effect against S. ampelimum, with half maximal effective concentration (EC50) values of 0.020 mg L-1. This strong activity rivals currently used commercial fungicides, such as Boscalid and Carbendazim, and has great potential as a lead compound for future development of novel fungicides.

Four- and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches

A highly efficient palladium-catalyzed fourfold tandem-domino reaction consisting of two carbopalladation and two C-H-activation steps was developed for the synthesis of two types of tetrasubstituted alkenes 3 and 6 with intrinsic helical chirality starting from substrates 1 and 4, respectively. A sixfold tandem-domino reaction was also developed by including a Sonogashira reaction. 20 compounds with different substitution patterns were prepared with yields of up to 97%. Structure elucidation by X-ray crystallography confirmed helical chirality of the two alkene moieties. Photophysical investigations of some of the compounds showed pronounced switching properties through light-controlled changes of their stereochemical configuration.

Synthesis and enantioselective hydrogenation of seven-membered cyclic imines: Substituted dibenzo[b,f][1,4]oxazepines

Highly enantioselective hydrogenation of seven-membered cyclic imines, substituted dibenzo[b,f][1,4]oxazepines, was achieved, with up to 94% ee, by using the [Ir(COD)Cl]2/(S)-Xyl-C3*-TunePhos complex as the catalyst in the presence of morpholine-HCl.