3169-77-5

Upstream product

• 583-78-8 2,5-dichlorophenol 
• 1493-27-2 ortho-nitrofluorobenzene 
• 88-73-3 2-Chloronitrobenzene 
• 3169-76-4 2,5-Dichlorophenyl o-nitrophenyl ether 

Downstream Products

• 89279-20-9 N,N-Dimethyl-N'-<2-(2,5-dichlorophenoxy)phenyl>-1,3-propanediamine 
• 89279-23-2 2-<2,5-Dichloro-N-<3-(dimethylamino)propyl>anilino>-phenol 
• 1596271-38-3 (E)-1-(2-(7-chloroquinolin-4-ylamino)ethyl)-3-(2-(2,5-dichlorophenoxy)phenyl)-2-phenylguanidine 
• 1596271-40-7 (E)-1-(3-(7-chloroquinolin-4-ylamino)propyl)-3-(2-(2,5-dichlorophenoxy)phenyl)-2-phenylguanidine 
• 1596271-43-0 (E)-2-(3-chlorophenyl)-1-(4-(7-chloroquinolin-4-ylamino)ethyl)-3-(2-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-46-3 (E)-2-(3-chlorophenyl)-1-(4-(7-chloroquinolin-4-ylamino)propyl)-3-(2-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-48-5 (E)-2-(3-chlorophenyl)-1-(4-(7-chloroquinolin-4-ylamino)butyl)-3-(2-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-49-6 (E)-2-(4-chlorophenyl)-1-(2-(7-chloroquinolin-4-ylamino)ethyl)-3-(2-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-51-0 (E)-2-(4-chlorophenyl)-1-(3-(7-chloroquinolin-4-ylamino)propyl)-3-(2-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-52-1 C₃₂H₂₇Cl₄N₅O 
• 1596271-13-4 1-(4-chlorophenyl)-3-(2-(2,5-dichlorophenoxy)phenyl)thiourea 
• 1596271-11-2 1-(3-chlorophenyl)-3-(2-(2,5-dichlorophenoxy)phenyl)thiourea 
• 1596271-09-8 1-(2-(2,5-dichlorophenoxy)phenyl)-3-phenylthiourea 

Relevant academic research and scientific papers

Pyrazinamide compounds and preparing method and application thereof and bactericide

The invention relates to the field of pesticide bactericides, and discloses a pyrazinamide compound and a preparing method and application thereof and a bactericide. The pyrazinamide compound has thestructure shown in the formula (I) or the formula (II) or the formula (III). According to the pyrazinamide compound and the preparing method and application thereof and the bactericide, by introducingpyrazine ring fragments and and diphenyl ether fragments with the wide biological activity in NNF-0721, and the pyrazinamide compound with the brand-new structure is designed; the pyrazinamide compound can serve as a brand-new succinodehydrogenase inhibitor or a bactericide. The formula is defined in the description.

DIARYL SUBSTITUTED HETEROAROMATIC COMPOUNDS

The invention relates to heterocyclic derivatives, to the use of said derivatives in treating a range of metabolic diseases and other conditions mediated by agonism of the G-protein coupled bile acid GPBAR1/TGR5 receptor, to compositions and formulations containing said derivatives, processes for their preparation and methods of delivery.

Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents

Synthesis and bioevaluation of new diaryl ether hybridized quinoline derivatives as antiplasmodial, antibacterial and antifungal agents is reported. It was encouraging to discover that several compounds displayed 2-3 folds better efficacy than chloroquine in chloroquine-resistant K1 strain of Plasmodium falciparum. Further, a few members of the library displayed good antibacterial efficacy against gram positive strains of bacteria but none of the compounds displayed any significant antifungal activity.