317322-37-5Relevant articles and documents
Facile and efficient total synthesis of (+)-preussin.
Lee,Kim,Oh,Ham
, p. 4041 - 4042 (2007/10/03)
[structure] The enantioselective total synthesis of (+)-preussin, a potent antifungal agent, has been achieved. The key steps are a Pd(0)-catalyzed oxazoline-forming reaction from L-phenylalanine, hydrogenolysis, and subsequent diastereoselective reductive cyclization of the intermediate aminoketone to pyrrolidine using Pearlman's catalyst.