317365-31-4 Usage
General Description
4-Cbz-2-(aminomethyl)morpholine, also known as 2-(aminomethyl)-4-(benzyloxycarbonyl)morpholine, is a chemical compound that belongs to the class of morpholine derivatives. It is a white to off-white solid that is primarily used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its structure consists of a morpholine ring with an aminoethyl side chain attached to the second carbon atom, and a benzyloxycarbonyl (Cbz) group attached to the nitrogen atom. 4-Cbz-2-(aMinoMethyl)Morpholine is commonly used as a reagent for the selective protection of amino groups in organic synthesis due to its stability under a wide range of reaction conditions. Additionally, it has been investigated for its potential biological activity and medicinal properties in the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 317365-31-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,7,3,6 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 317365-31:
(8*3)+(7*1)+(6*7)+(5*3)+(4*6)+(3*5)+(2*3)+(1*1)=134
134 % 10 = 4
So 317365-31-4 is a valid CAS Registry Number.
317365-31-4Relevant articles and documents
Disubstituted pyrimidines as Lck inhibitors
Hunt, Julianne A.,Beresis, Richard T.,Goulet, Joung L.,Holmes, Mark A.,Hong, Xinfang J.,Kovacs, Ernest,Mills, Sander G.,Ruzek, Rowena D.,Wong, Frederick,Hermes, Jeffrey D.,Park, Young-Whan,Salowe, Scott P.,Sonatore, Lisa M.,Wu, Lin,Woods, Andrea,Zaller, Dennis M.,Sinclair, Peter J.
supporting information; experimental part, p. 5440 - 5443 (2010/04/26)
We have developed a family of 4-benzimidazolyl-N-piperazinethyl-pyrimidin-2-amines that are subnanomolar inhibitors of Lck. A subset of these Lck inhibitors, with heterocyclic substituents at the benzimidazole C5, are also low-nanomolar inhibitors of cell