3175-95-9

Usage

Uses

Given the provided materials, there are no specific applications listed for deoxyaconitine. However, it is important to note that due to its high toxicity and potential for harm, deoxyaconitine is not recommended for any therapeutic or industrial use. Its primary classification is as a controlled substance, emphasizing the need for strict regulation and caution in handling to prevent accidental exposure or misuse.

InChI:InChI=1/C34H47NO10/c1-7-35-16-31(17-40-3)14-13-21(41-4)33-20-15-32(39)28(44-30(38)19-11-9-8-10-12-19)22(20)34(45-18(2)36,27(37)29(32)43-6)23(26(33)35)24(42-5)25(31)33/h8-12,20-29,37,39H,7,13-17H2,1-6H3/t20-,21-,22+,23?,24-,25+,26?,27-,28+,29-,31-,32-,33?,34+/m0/s1

Upstream product

• 139617-11-1 3-O-(S-methyl)thiocarbonylaconitine 
• 121220-90-4 3-O-(imidazolylthiocarbonyl)-aconitine 
• 302-27-2 indaconitine 
• 302-27-2 aconitine 

Relevant academic research and scientific papers

Aconitine compounds and analgesic/anti-inflammatory agent containing the same

Novel aconitine compounds of the formula STR1 wherein the symbols are as defined in the description, as well as analgesic/anti-inflammatory agent containing them or salts thereof as active ingredient.

Aconitine compounds and analgesic/anti-inflammatory agent containing the same

Novel aconitine compounds of the formula STR1 wherein the symbols are as defined in the description, as well as analgesic/anti-inflammatory agent containing them or salts thereof as active ingredient.

NOVEL ACONITINE COMPOUND AND ANALGESIC/ANTIINFLAMMATORY AGENT

A novel aconitine compound represented by general formula (I) and analgesic/antiinflammatory agent containing said compound or its salt as the active ingredient; wherein each symbol is as defined in the text of specification.

Studies on Aconitum species. XV. Deoxygenation reaction of aconitine type alkaloids

Mesaconitine (1) in tetrahydrofuran reacted with sodium hydride, a catalytic amount of imidazole, carbon disulfide and methyl iodide at room temperature to give the di-O-(S-methyl)thiocarbonate (5). The reductive cleavage of 5 with tri-n-butyltin hydride

DEOXYGENATION REACTIONS OF C19-DITERPENOID ALKALOIDS

Efficient methods for deoxygenation of secondary and tertiary alcohols of some C19-diterpenoid alkaloids are presented.Delphisine (12) was converted to 1-deoxydelphisine (19) via either 1,2-pyrodelphisine (17) or phenyl thionocarbonate 20.The following alkaloids were deoxygenated via their thiocarbonylimidazolyl derivatives: 14-acetyldelcosine (13) to 14-acetyl-1-deoxydelcosine (22); alkaline hydrolysis of 22 gave 1-deoxydelcosine (23); aconitine (24) to 3-deoxyaconitine (27); yunaconitine (25) to crassicauline A (28).Deoxygenation of 14-acetyldictyocarpine (30) via the chloro-derivate 31 gave 14-acetyl-10-deoxydictiocarpine (34).Reduction of 31 with LiAlH4 gave the unusual elimination product 32.An improved partial synthesis of hypaconitine (35) from aconitine (24) is also presented.