3176-55-4

Usage

Chemical Family

Thiadiazoleamines

Explanation

The compound belongs to a group of chemical compounds known as thiadiazoleamines, which are characterized by the presence of a thiadiazole ring and an amine group.

Explanation

The compound features a fused ring system consisting of a triazole and a thiadiazole, which are both heterocyclic rings containing nitrogen and sulfur atoms.

Explanation

The compound has a substituted phenyl group (4-methylphenyl) attached to the 3rd position of the triazolo-thiadiazole ring, which introduces a methyl group on the para position of the phenyl ring.

Explanation

The compound contains an amine group (-NH2) attached to the 6th position of the triazolo-thiadiazole ring, which is a basic functional group containing a nitrogen atom bonded to two hydrogen atoms.

Explanation

Due to its unique chemical structure, the compound may have potential applications in the development of new drugs with therapeutic properties, although further research and experimentation are required to determine its specific uses.

Explanation

The precise characteristics and potential uses of the compound would need to be explored through additional research and experimentation to fully understand its properties and potential applications.

Ring Structure

Triazolo-thiadiazole

Substitution

3-(4-methylphenyl)

Functional Group

Amine

Potential Applications

Pharmaceutical Industry

Further Investigation

Research and Experimentation

Upstream product

• 506-68-3 bromocyane 
• 13229-01-1 3-(4-methylphenyl)-4-amino-5-mercapto-1,2,4-triazole 
• 13229-01-1 4-amino-2,4-dihydro-5-(4-methylphenyl)-3H-1,2,4-triazole-3-thione 

Relevant academic research and scientific papers

Synthesis, characterization and fungitoxicity of 3,4,6-triayl-striazolo [3,4-b]-1,3,4-thiadiazolo [1,3,5]-triazine-5-thiones

In the present work 3,4,6-triayl-s-triazolo [3,4-b]-1,3,4-thiadiazolo [1,3,50-triazine-5-thiones (IVan) were synehsized by 4+2 cycloaddition of 6-arylidine amino-3-aryl-s-triazolo [3,4-b]-1,3,4-thiadiazoles (IIIa-n) are arylisothiocynate in dry tolune as solvent. 6-Arylidine amino-3-aryl-s-triazolo [3,4-b]-1,3,4-thiadiazoles (IIIa-n) were prepared from aromatic aldehyde refluxing in absolute ethanol with 6-amino-3-aryl-s-triazole [3,4-b]-1,3,4-thiadiazoles (IIa-g), which are prepared from 3-aryl, 4-amino-5-mercaptos-triazole (Ia-g) by treating it with cyanogen bromide in ethanol. Starting material 3-aryl, 4-amino-5-mercapto-s-triazoles (Ia-g) wre prepred in excellent yield following the method of Ried and Heindel1. The reaction sequence leading to the formation of titled compounds are given in the scheme 1. All the synthesized fourteen titled compounds were well characterized by their analytical and spectral data. Fungitoxicity of titled compounds (IVa-n) have been evaluated against two fungal species i.e. Helminthosporium orayzee and Alternaria solanai.

Synthesis of Heterocycles. Part VII . Synthesis and Antimicrobial Activity of Some 7H-s-Triazolothiadiazine and s-Triazolothiadiazole Derivatives

The cyclization of 4-amino-5-aryl-3-cyanomethylthio-1,2,4-triazoles II in the presence of concentrated sulfuric acid yields 7H-6-amino-s-triazolothiadiazines III.Cyclization of 4-amino-5-aryl-1,2,4-triazole-3-thiones I with phenacyl chloride yields 7H-3-aryl-6-phenyl-s-triazolothiadiazines IV.Similarly, compounds I condensed with cyanogen bromide, phenyl isothiocyanate and carbon disulfide to give the corresponding cyclized products 6-amino-3-aryl-s-triazolothiadiazoles V, 3-aryl-6-phenylamino-s-triazolothiadiazoles VI and 3-aryl-s-triazolothiadiazol-6(5H)thiones VII, respectively.Also in the presence of phosphoryl chloride, compounds I underwent cyclization with monocarboxylic acids and oxalic acid to 3,6-diaryl-s-triazolothiadiazole VIII and 6,6'-bis(3-aryl-s-triazolothiadiazoles) IX.The above compounds were screened for their antimicrobial activity.