317806-86-3

Basic information

• Product Name: 5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE
• Synonyms: 3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-AMINE;5-AMINO-3-T-BUTYL-N-P-TOLYL-PYRAZOLE;5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE HCl;3-tert-Butyl-1-(4-methylphenyl)-1H-pyrazol-5-amine hydrochloride;3-tert-Butyl-1-(p-tolyl)-1H-pyrazol-5-amine hydrochloride;(1:1)3-tert-butyl-1-p-tolyl-1H-pyrazol-5-aMine;1H-Pyrazol-5-aMine, 3-(1,1-diMethylethyl)-1-(4-Methylphenyl)-,Monohydrochloride;1H-Pyrazol-5-aMine, 3-(1,1-diMethylethyl)-1-(4-Methylphenyl)-, hydrochloride (1:1)
• CAS NO: 317806-86-3
• Molecular Formula: C14H19N3
• Molecular Weight: 265.78
• Mol File: 317806-86-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 195℃(DEC.)
• Boiling Point: 368.3 °C at 760 mmHg
• Flash Point: 176.5 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE(317806-86-3)
• EPA Substance Registry System: 5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE(317806-86-3)

Safety Data

• Hazardous Substances Data: 317806-86-3(Hazardous Substances Data)

Usage

General Description

5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE is a chemical compound with a complex molecular structure. It is a pyrazole derivative that features a tert-butyl group and a p-tolyl group attached to the pyrazole ring. 5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YLAMINE has potential applications in pharmaceutical research and organic synthesis due to its unique structure and potential biological activities. It may be used as a building block in the development of novel drugs and pharmaceutical compounds. The compound's specific properties and potential uses would need to be further investigated and evaluated through scientific research and experimentation.

Upstream product

• 59997-51-2 trimethylacetylacetonitrile 
• 637-60-5 p-tolylhydrazine hydrochloride 

Downstream Products

• 285984-47-6 [5-tert-butyl-2-(4-methylphenyl)-2H-pyrazol-3-yl]carbamic acid phenyl ester 
• 1082296-42-1 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(4-methyl-3-nitrophenyl)urea 

Relevant articles and documents

ANTI-MUCUS DRUGS AND USES THEREFOR

Disclosed are methods of identifying, generating and synthesizing compounds that inhibit MAPK13 activity. In various embodiments, compounds, salts thereof and prodrugs thereof of the present teachings can be useful for the treatment of diseases and disord

2,3-DIHYDRO-1H-INDENE-2-YL UREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME

A 2,3-dihydro-1H-indene-2-yl urea derivative represented by Formula (Ia) or a pharmaceutically acceptable salt thereof:

Microwave-assisted synthesis of N-pyrazole ureas and the p38α inhibitor BIRB 796 for study into accelerated cell ageing

Microwave irradiation of substituted hydrazines and β-ketoesters gives 5-aminopyrazoles in excellent yield, which can be transformed to the corresponding N-carbonyl derivatives by treatment with an isocyanate or chloroformate. Derivatization of 4-nitronaphth-1-ol using predominantly microwave heating methods and reaction with an N-pyrazole carbamate provides a rapid route to the N-pyrazole urea BIRB 796 in high purity, as a potent and selective inhibitor of p38α mitogen-activated protein kinase for the study of accelerated ageing in Werner syndrome cells. The Royal Society of Chemistry 2006.