31788-88-2 Usage
Uses
Used in Pharmaceutical Industry:
(2-AMINO-2-PHENYLETHYL)DIMETHYLAMINE is used as a building block for the synthesis of pharmaceutical compounds due to its unique structure and reactivity. It contributes to the development of new drugs by providing a foundation for chemical reactions that lead to the creation of therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, (2-AMINO-2-PHENYLETHYL)DIMETHYLAMINE serves as an intermediate in the production of various agrochemicals. Its properties allow it to be incorporated into the synthesis of pesticides, herbicides, and other agricultural chemicals, enhancing their effectiveness and selectivity.
Used in Research and Development:
(2-AMINO-2-PHENYLETHYL)DIMETHYLAMINE is utilized in research and development as a potential precursor for the discovery of new applications. Its unique chemical structure offers opportunities for innovation in various fields, including materials science, chemical engineering, and biotechnology. Researchers are exploring its potential to create novel compounds with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 31788-88-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,7,8 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 31788-88:
(7*3)+(6*1)+(5*7)+(4*8)+(3*8)+(2*8)+(1*8)=142
142 % 10 = 2
So 31788-88-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H16N2/c1-12(2)8-10(11)9-6-4-3-5-7-9/h3-7,10H,8,11H2,1-2H3/p+2/t10-/m0/s1
31788-88-2Relevant academic research and scientific papers
α-Methylation at benzylic fragment of N-aryl-N′-benzyl ureas provides TRPV1 antagonists with better pharmacokinetic properties and higher efficacy in inflammatory pain model
Gomtsyan, Arthur,Bayburt, Erol K.,Keddy, Ryan,Turner, Sean C.,Jinkerson, Tammie K.,Didomenico, Stanley,Perner, Richard J.,Koenig, John R.,Drizin, Irene,McDonald, Heath A.,Surowy, Carol S.,Honore, Prisca,Mikusa, Joe,Marsh, Kennan C.,Wetter, Jill M.,Faltynek, Connie R.,Lee, Chih-Hung
, p. 3894 - 3899 (2008/02/09)
SAR studies for N-aryl-N′-benzyl urea class of TRPV1 antagonists have been extended to cover α-benzyl alkylation. Alkylated compounds showed weaker in vitro potencies in blocking capsaicin activation of TRPV1 receptor, but possessed improved pharmacokinetic properties. Further structural manipulations that included replacement of isoquinoline core with indazole and isolation of single enantiomer led to TRPV1 antagonists like (R)-16a with superior pharmacokinetic properties and greater potency in animal model of inflammatory pain.
