31789-95-4Relevant academic research and scientific papers
REACTIONS OF IMIDIC ACID DERIVATIVES WITH NUCLEOPHILIC REAGENTS. KINETICS OF THE REACTION OF N-SUBSTITUTED BENZIMIDOYL CHLORIDES WITH ARYLAMIDES IN APROTIC MEDIA. THE EFFECT OF THE STRUCTURE OF THE AMINE
Litvinenko, L. M.,Mikhailov, V. A.,Drizhd, L. P.,Savelova, V. A.,Kryuchkova, E. N.
, p. 1139 - 1143 (2007/10/02)
The kinetics of the reaction of primary aromatic amines H2NC6H4X with N-substituted benzimidoyl chlorides C6H5C(Cl)=NR in acetonitrile (R = CH3; COC6H5, SO2C6H5) and dioxane (R = CH3) at 25 grad C were studied.The sensitivity of the rate of the processes to variation in the substituent X in the arylamine depends substantially on the electronic nature of the substituent R in the in the imidoyl chloride, but isoparametric effects are not observed.It is supposed that this is due to the realization of a mechanism of bimolecular nucleophilic substitution at the imidoyl carbon atom through various transition states, depending on the substituent R at C=N bond.
