3180-77-6

Usage

General Description

1-hexopyranosylpyrimidine-2,4(1H,3H)-dione is a chemical compound with the molecular formula C12H16N2O6. It is a pyrimidine derivative and contains a hexopyranose sugar moiety. 1-hexopyranosylpyrimidine-2,4(1H,3H)-dione is not naturally occurring and is typically synthesized in a laboratory setting. It has potential applications in the field of medicinal chemistry, particularly in the development of nucleoside analogs and antiviral drugs. The chemical structure of 1-hexopyranosylpyrimidine-2,4(1H,3H)-dione features a pyrimidine ring with a sugar group attached, and it may exhibit biological activity that could be of interest for further research and development.

Upstream product

• 23707-29-1 1-(Tetra-O-acetyl-β-D-glucopyranosyl)-4-ethoxy-2(1H)-pyrimidon 
• 4603-96-7 4-methoxy-1-(tetra-O-acetyl-β-D-glucopyranosyl)-1H-pyrimidin-2-one 
• 604-69-3 β-D-glucose pentaacetate 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 121654-00-0 3,4,6-tris-O-tert-butyldimethylsilyl-1,2-anhydro-α-D-glucopyranose 
• 3180-73-2 1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)uracil 

Relevant academic research and scientific papers

Synthesis and Conformational Analysis of 2-O-Silyl Protected Nucleosides from Unprotected Nucleobases and Sugar Epoxides

Synthesis of orthogonally protected 2-silyl nucleosides were achieved by trans opening of sugar epoxides with nucleobases catalyzed by trimethylsilyltrifluoromethanesulfonate using hexamethyldisilazane both as solvent and silylating agent. Both α and β nu

Morpholino-subunit combinatorial library and method

A method of generating a compound capable of interacting specifically with a selected macromolecular ligand is disclosed. The method involves contacting the ligand with a combinatorial library of oligomers composed of morpholino subunits with a variety of nucleobase and non-nucleobase side chains. Oligomer molecules that bind specifically to the receptor are isolated and their sequence of base moieties is determined. Also disclosed is a combinatorial library of oligomers useful in the method and novel morpholino-subunit polymer compositions.

SYNTHESE ET ETUDE CONFORMATIONELLE PAR R.M.N.-13C DE β-NUCLEOSIDES PYRIMIDIQUES CONTENANT UNE OU DEUX SOUSUNITES HEXOPYRANOSYLES: APPLICATION A LA CONFORMATION DE L'ANTHELMYCINE

Several new peracetylated pyrimidine N-1 nucleosides containing one two β-D-hexopyranosyl residues have been synthesized and their physical characteristics are reported.The conformation of these nucleosides has been investigated by highresolution 13C-n.m.r. analysis after deblocking.It was poddible to distinguish between the syn and anti rotamers of 3-β-D-glucopyranosyluracyl, and to establish the favored anti conformation in solution of the nucleoside disaccharide, antibiotic anthelmycin.