318261-63-1Relevant academic research and scientific papers
N,N,N',N'-TETRAPHENYL BENZIDINE COMPOUND
-
Paragraph 0098; 0099, (2020/04/16)
PROBLEM TO BE SOLVED: To provide an N,N,N',N'-tetraphenyl benzidine compound to be used as a source material of a polymer containing a fluorine atom suitable for a charge transporting varnish that gives a thin film, with which an organic EL element having excellent luminance characteristics can be achieved, even when the film is used as a single layer in a state of disposed between and in contact with an anode and a luminescent layer. SOLUTION: The N,N,N',N'-tetraphenyl benzidine compound is represented by formula (9-1). In the formula, Z2 represents an alkoxy group having 1 to 20 carbon atoms which may include an ether bone, however, Z2 as a methoxy group or n-octyloxy group substituted at a para-position of an amino group is excluded. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT
MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE
-
Paragraph 00754, (2019/03/05)
The present disclosure provides for compounds of Formula (I) wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).
Staudinger-phosphonite reactions for the chemoselective transformation of azido-containing peptides and proteins
Vallee, M. Robert J.,Majkut, Paul,Wilkening, Ina,Weise, Christoph,Mueller, Gregor,Hackenberger, Christian P. R.
supporting information; experimental part, p. 5440 - 5443 (2011/12/04)
Site-specific functionalization of proteins by bioorthogonal modification offers a convenient pathway to create, modify, and study biologically active biopolymers. In this paper the Staudinger reaction of aryl-phosphonites for the chemoselective functiona
Solvophobically driven π-stacking of phenylene ethynylene macrocycles and oligomers
Lahiri,Thompson,Moore
, p. 11315 - 11319 (2007/10/03)
Phenylene ethynylene macrocycles and oligomers with three different side-chain linking groups (ester, benzyl ether, and phenyl ether) were synthesized to investigate their tendency to undergo solvent induced π-stacked organization. 1H NMR, UV, and fluorescence spectroscopies were used to probe two types of π-stacked supramolecular organizations: the intramolecular conformational ordering of the oligomers, and the intermolecular aggregation of the macrocycles. One important conclusion is that solvent can play a very dramatic role in modulating the strength of the interactions that drive the association of these π-stacked structures. The other important conclusion is that in a given solvent, the nature of the side chain linking group strongly influences the π-stacking propensities. It was found that macrocycles and oligomers with the ester side chain linking group were prone to adopt π-stacked structures in a range of solvents, whereas the corresponding macrocycles with benzyl ether and phenyl ether side chain linking groups showed only limited ability to π-stack, even in the most polar solvent examined (DMSO). In the interest of manipulating the helix-coil folding transition of phenylene ethynylene oligomers, a heterosequence consisting of monomers with ester and benzyl ether side chain linkages was synthesized. The folding transition of the heterooligomer was intermediate to that observed for the corresponding homooligomers, suggesting that the backbone sequence can be used to tune the stability of conformations that are based on π-stacked organizations.
