Basic information

Product Name: Amiodarone N-oxide
Synonyms: Amiodarone N-oxide;(2-Butyl-3-benzofuranyl)[4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl]methanone;(2-Butyl-3-benzofuranyl)[4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl]methanone N-oxide
CAS NO:318267-30-0
Molecular Formula: C25H29I2NO4
Molecular Weight: 661.31
EINECS: N/A
Product Categories: Amiodarone
Mol File: 318267-30-0.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
PKA: 4.88±0.50(Predicted)
CAS DataBase Reference: Amiodarone N-oxide(CAS DataBase Reference)
NIST Chemistry Reference: Amiodarone N-oxide(318267-30-0)
EPA Substance Registry System: Amiodarone N-oxide(318267-30-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 318267-30-0(Hazardous Substances Data)

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Usage
SDS
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318267-30-0 Usage

Uses

Used in Cardiology:
Amiodarone N-oxide is used as an antiarrhythmic agent for the treatment of various cardiac arrhythmias. Its class III antiarrhythmic activity helps in prolonging the action potential duration and refractory period of cardiac cells, thereby stabilizing the heart rhythm.
Used in Drug Monitoring:
Monitoring of amiodarone N-oxide levels in patients undergoing amiodarone therapy is used to minimize the risk of toxicity. As it is known to have potential toxic effects, including pulmonary toxicity, hepatotoxicity, and thyroid dysfunction, regular assessment of its levels can help in adjusting the dosage and preventing adverse effects.

Check Digit Verification of cas no

The CAS Registry Mumber 318267-30-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,8,2,6 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 318267-30:
(8*3)+(7*1)+(6*8)+(5*2)+(4*6)+(3*7)+(2*3)+(1*0)=140
140 % 10 = 0
So 318267-30-0 is a valid CAS Registry Number.

318267-30-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	Amiodarone N-oxide

1.2 Other means of identification

Product number	-
Other names	(2-Butyl-3-benzofuranyl)[4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl]methanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:318267-30-0 SDS

318267-30-0Upstream product

318267-30-0Downstream Products

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