318464-23-2

Usage

Uses

Used in Pharmaceutical Industry:
(3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester is used as a building block for the synthesis of various drugs and pharmaceutical compounds. Its unique functional groups allow for the creation of diverse molecular structures with potential therapeutic applications.
Used in Organic Synthesis:
(3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester is used as a versatile intermediate in organic synthesis, enabling the development of new chemical entities with specific properties and functions.
Used as a Prodrug:
(3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester is used as a prodrug, allowing for improved delivery and absorption in the body. Its ester functionality can be hydrolyzed to release the active drug, enhancing bioavailability and therapeutic efficacy.

Upstream product

• 341973-08-8 (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 34619-03-9 tert-butyldicarbonate 

Downstream Products

• 341973-08-8 (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride 

Relevant academic research and scientific papers

DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT

The present invention relates to a diketohydrazine derivative of formula (I) and a pharmaceutically acceptable salt thereof (the symbols in the formula have the same meaning as described in the specification). The compound of formula (I) has an inhibitory activity against cysteine protease, and it is useful for the treatment of inflammatory diseases, immune diseases, ischemic diseases, respiratory diseases, circulatory diseases, blood diseases, neuronal diseases, hepatic or biliary diseases, osseous or articular diseases, metabolic diseases, etc. And the compound has inhibitory activity against elastase and it is also useful for the treatment of COPD (chronic obstacle pulmonary diseases).

Oxadiazole derivative compounds and drugs containing these compounds as the active ingredient

An oxadiazole derivative of formula (I) and a non-toxic salt thereof, wherein all symbols have the same meaning as described in the specification. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful

Oxadiazole derivatives and drugs containing these derivatives as the active ingredient

An oxadiazole derivative of formula (I) and a non-toxic salt thereof, wherein R is hydrogen, alkyl, CycA, etc.; AA1 is a single bond, amino acid residue, etc.; AA2 is a single bond, amino acid residue, etc.; R7 and R8 are hydrogen, alkyl, etc.; R9 is hydrogen, alkyl, etc.; R10 is hydrogen, alkyl, etc.). The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation system disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.

1,3,4-Oxadiazoline derivatives and drugs containing these derivatives as active ingredient

A 1,3,4-oxadiazoline derivative of formula (I) , wherein W is oxygen, sulfer; R is hydrogen, alkyl, CycA, etc.; AA1 is a single bond, amino acid residue, etc.; AA2 is a single bond, amino acid residue, etc.; R7 and R8 are hydrogen, alkyl, etc.; R9 is hydrogen, alkyl, etc., and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.