318464-33-4Relevant academic research and scientific papers
Process for the preparation of a taxane derivative
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Page/Page column 6-7; 10; 14, (2008/06/13)
The invention relates to an improved process for the synthesis of 13-(N-Boc-β-isobutylserinyl)-14-β-hydroxybaccatin III-1,14-carbonate (I), wherein carbonation of the 1,14-hydroxy groups of the baccatin skeleton is carried out with bis(trichloromethylcarb
Process for the preparation of a taxane derivative
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Page/Page column 5-6; 8; 10-11, (2008/06/13)
The invention relates to an improved process for the synthesis of 13-(N-Boc-β-isobutylserinyl)-14-β-hydroxybaccatin III-1,14-carbonate (I), wherein carbonation of the 1,14-hydroxy groups of the baccatin skeleton is carried out with bis(trichloromethylcarb
TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
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Page 5-10; 17, (2008/06/13)
The invention discloses an oxazolidine intermediate for the synthesis of 14- beta -hydroxy-1,14-carbonate-baccatines bearing a 13-isoserine substituent, and a process for the preparation thereof.
