318974-80-0Relevant articles and documents
A straightforward synthesis of protected isostatine from achiral precursors using the asymmetric chelate claisen rearrangement
Kazmaier, Uli,Krebs, Achim
, p. 479 - 482 (2007/10/03)
Starting from achiral TFA-protected glycine crotyl ester (3) the interesting, suitable protected, enantiomerically pure β-hydroxy-γ-amino isostatine (7) was synthesized in only four steps. The amino acid obtained can directly be introduced into peptides.