3191-48-8Relevant academic research and scientific papers
Mild synthesis of N′-aryl-N,N-dimethylformamidinium chloride by Vilsmeier-Haack reagent
Meng, Ge,Sha, Yao Wu,Zhang, Rui,Bai, Nan
experimental part, p. 1043 - 1046 (2012/06/01)
Formamidine derivatives could be used as the building blocks for substituted heterocyclic compounds with various biological activities. N′-Aryl-N,N-dimethylformamidinium chlorides have been synthesized in high yields by reaction of aromatic primary amines with Vilsmeier-Haack reagent at room temperature. The structures of all the new compounds were identified by ESI-MS, IR and NMR spectra. The steric structures of some of these compounds were clarified by X-ray single crystal analysis.
