319432-08-1Relevant academic research and scientific papers
Furan ring opening-indole ring closure: Synthesis of furo[2′, 3′:3,4]-cycloheota[1,2-b]indolium chlorides
Butin, Alexander V.,Smirnov, Sergey K.,Stroganova, Tatyana A.
, p. 623 - 628 (2007/10/03)
A new synthetic approach to furo[2′,3′:3,4]cyclohepta[1,2-b] indolium chlorides is elaborated starting from 2-acetylaminoaryldifurylmethanes or 2-aminoaryldifurylmethanes under treatment with methanolic HCl solution. The reaction proceeds in three steps: recyclization, intramolecular cyclization, and disproportionation. In this case the furan ring takes part in building up both pyrrole and seven-membered rings. The same salts can be obtained directly from 2-acetylaminobenzaldehydes and 2-methylfuran under similar conditions without isolation of corresponding 2-acetylaminoaryldifurylmethanes.
Furyl(aryl)methanes and their derivatives. Part 21: Cinnnoline derivatives from 2-aminophenylbisfurylmethanes
Abaev, Vladimir T.,Gutnov, Andrey V.,Butin, Alexander V.,Zavodnik, Valerij E.
, p. 8933 - 8937 (2007/10/03)
(Z)-4-[4-(5-Methyl-2-furyl)-3-cinnolinyl]-3-buten-2-ones and (Z)-1-[4-(5-ethyl-2-furyl)-3-cinnolinyl]-1-penten-3-ones have been obtained from 2-aminoarylbisfurylmethanes under treatment with isoamyl nitrite/trimethylchlorosilane in dry acetonitrile. Intra
