319473-24-0

Basic information

• Product Name: 4-bromo-2-chloro-5-methylphenol
• Synonyms: 4-bromo-2-chloro-5-methylphenol
• CAS NO: 319473-24-0
• Molecular Formula: C₇H₆BrClO
• Molecular Weight: 221.47894
• Mol File: 319473-24-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 70-70.5 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 260.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.674±0.06 g/cm3(Predicted)
• PKA: 8.05±0.23(Predicted)
• CAS DataBase Reference: 4-bromo-2-chloro-5-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-chloro-5-methylphenol(319473-24-0)
• EPA Substance Registry System: 4-bromo-2-chloro-5-methylphenol(319473-24-0)

Safety Data

• Hazardous Substances Data: 319473-24-0(Hazardous Substances Data)

Upstream product

• 615-74-7 2-chloro-5-methylphenol 

Downstream Products

• 1115234-57-5 4-bromo-2-dodecyl-5-methylphenol 
• 1115234-61-1 C₃₁H₅₆O 
• 511295-15-1 5'-chloro-2'-[2-(3'-chloro-5'-[1,3]dioxan-2-yl-6,2'-dimethoxy-biphenyl-3-yl)-ethyl]-2,4'-dimethoxy-biphenyl-4-carboxylic acid methyl ester 
• 511295-13-9 5'-chloro-2'-[2-(5'-[1,3]dioxan-2-yl-6,2'-dimethoxy-biphenyl-3-yl)-ethyl]-2,4'-dimethoxy-biphenyl-4-carboxylic acid methyl ester 
• 511295-18-4 5-chloro-5'-[2-(5-chloro-4'-hydroxymethyl-4,2'-dimethoxy-biphenyl-2-yl)-ethyl]-6,2'-dimethoxy-biphenyl-3-carbaldehyde 
• 511295-16-2 5'-[2-(5-chloro-4'-hydroxymethyl-4,2'-dimethoxy-biphenyl-2-yl)-ethyl]-6,2'-dimethoxy-biphenyl-3-carbaldehyde 
• 511295-09-3 (3-chloro-4-methoxy-6-methylphenyl)boronic acid 
• 179897-95-1 1-bromo-5-chloro-4-methoxy-2-methylbenzene 

Relevant articles and documents

A convenient and regioselective oxidative bromination of electron-rich aromatic rings using potassium bromide and benzyltriphenylphosphonium peroxymonosulfate under nearly neutral reaction conditions

Regioselective oxidative bromination of electron-rich aromatic rings has been studied using potassium bromide as a bromine source in the presence of benzyltriphenylphosphonium peroxymonosulfate as oxidant under nearly neutral reaction conditions. In most cases we obtained monobrominated derivatives regioselectively and in good to high yields without the aid of strong acids.

A controlled and selective bromination of phenols by benzyltriphenylphosphonium tribromide

Reactions of phenols with benzyltriphenylphosphonium tribromide in dichloromethane-methanol mixture (2:1) gave mono, di and tri brominated phenols at room temperature with high selectivity and good yields.