3199-44-8

Basic information

• Product Name: THIOPHENE-3-CARBOXALDEHYDE DIETHYL ACETAL
• Synonyms: THIOPHENE-3-CARBOXALDEHYDE DIETHYL ACETAL;3-(diethoxymethyl)thiophene
• CAS NO: 3199-44-8
• Molecular Formula: C₉H₁₄O₂S
• Molecular Weight: 186.27
• Mol File: 3199-44-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 130°C 30mm
• Flash Point: 130°C/30mm
• Appearance: /
• Density: 1.066g/cm³
• Vapor Pressure: 0.148mmHg at 25°C
• Refractive Index: 1.4865
• Water Solubility: Insoluble in water.
• BRN: 125429
• CAS DataBase Reference: THIOPHENE-3-CARBOXALDEHYDE DIETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: THIOPHENE-3-CARBOXALDEHYDE DIETHYL ACETAL(3199-44-8)
• EPA Substance Registry System: THIOPHENE-3-CARBOXALDEHYDE DIETHYL ACETAL(3199-44-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 3199-44-8(Hazardous Substances Data)

Usage

Uses

Thiophene-3-carboxaldehyde diethyl aceta is used in OLED materials. Also used as electronic intermediate.

InChI:InChI=1/C9H14O2S/c1-3-10-9(11-4-2)8-5-6-12-7-8/h5-7,9H,3-4H2,1-2H3

Upstream product

• 498-62-4 3-thiophene carboxaldehyde 
• 122-51-0 orthoformic acid triethyl ester 
• 10486-61-0 3-thienyl iodide 

Downstream Products

• 1215859-23-6 2-(4-formylthiophen-2-yl)benzaldehyde 
• 1215859-13-4 2-(2-formylphenyl)thiophene-3-carbaldehyde 
• 1215859-24-7 2-(3-formylthiophen-2-yl)benzonitrile 
• 1215859-14-5 2-(3-formylthiophen-2-yl)benzonitrile 
• 1215859-07-6 4-(3-formylthiophen-2-yl)-benzonitrile 
• 1215859-17-8 4-(4-formylthiophen-2-yl)-benzonitrile 
• 1215859-12-3 3-(3-formylthiophen-2-yl)benzonitrile 
• 1215859-22-5 3-(4-formylthiophen-2-yl)benzonitrile 

Relevant articles and documents

Construction of complex bisether-bridged medium-sized cyclic compounds from o-(1-(acyloxy)propargyl)benzaldehydes under base and acid catalysis

We report herein our serendipitous discovery of the rapid and straightforward accesses to unprecedented diverse complex molecular structures from readily available starting materials. Catalyzed by 1,8-diazabicyclo[5.4.0]undec-7-ene under mild conditions, o-(1-(acyloxy)propargyl)benzaldehydes 1 underwent efficient and selective dimerization reactions to produce novel complex bisether-bridged tricyclic products 3 and 4. The reactions proceeded most probably through dimerizations between 3-methylene-3H-isochromene intermediate and its zwitterionic resonance structures which were generated from a concerted 6-πelectrocyclic ring closure reaction from the initially formed (2-formylphenyl)allene intermediates derived directly from o-(1-(acyloxy)propargyl)benzaldehydes. Treatment of the resulting product simply with NaOEt in ethanol and aqueous HCl, respectively, enabled further development of complex molecular diversities.