319919-34-1Relevant articles and documents
Synthesis and evaluation of anti-HIV-1 activity of 3′-azido-3′-deoxy-2′-O,4′-C-methylene-linked bicyclic thymine nucleosides
Olsen, Anne G.,Rajwanshi, Vivek K.,Nielsen, Claus,Wengel, Jesper
, p. 3610 - 3614 (2007/10/03)
The two conformationally locked AZT analogues 4 and 5, each containing a 2′-O,4′-C-methylene-linked bicyclic furanose moiety, are synthesized via the 3′-azido-3′-deoxy-4′-C-hydroxymethyl nucleoside 16. The β-D-ribo-configured derivative 4 is shown by NOE