3201-28-3Relevant academic research and scientific papers
SUBSTITUTED BENZENE AND 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS
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Paragraph 0532; 0535-0536, (2016/05/02)
The present invention relates to substituted benzene compounds and bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
A one-pot process for the regioselective synthesis of 1,3,4-trisubstituted-1H-pyrazoles
Raw, Steven A.,Turner, Andrew T.
experimental part, p. 696 - 699 (2011/02/27)
This Letter reports a facile and regioselective one-pot synthesis of 1,3,4-trisubstituted-1H-pyrazoles. It comprises a three-step telescoped sequence, which has been utilised in the production of a variety of differentially substituted pyrazoles.
Unambiguous synthesis of 1-methyl-3-hydroxypyrazoles
Zimmermann, Diane,Krogsgaard-Larsen, Povl,Ehrhardt, Jean-Daniel,Madsen, Ulf,Janin, Yves L.
, p. 9393 - 9400 (2007/10/03)
2,3-Dihydropyrazolo[3,2-b]oxazoles were used as intermediates in a new method for preparation of N1-methyl-3-hydroxypyrazoles. Synthesis of this bicyclic system was achieved either by alkylation of 3-hydroxypyrazole with 1,2-dibromoethane or, with better
PHOTOCHEMICAL BENZYL MIGRATION IN 3-PYRAZOLIN-5-ONES
Singh, Gurbakhsh,Singh, Devender,Ram, Ram Nath
, p. 2213 - 2216 (2007/10/02)
The 3-pyrazolin-5-ones (1) undergo light induced rearrangement by N -> O and N -> C4 benzyl migrations.A free radical mechanism is proposed.
