320337-16-4 Usage
Uses
Used in Pharmaceutical Industry:
2-(Isopropylsulfonyl)ethanamine is utilized as a precursor in the synthesis of a range of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows it to be a key component in the creation of molecules with specific medicinal properties.
Used in Agrochemical Production:
In the agrochemical sector, 2-(Isopropylsulfonyl)ethanamine is employed in the production of insecticides and fungicides. Its role in these products is to help control and manage pests and diseases that affect crops, thereby contributing to increased agricultural productivity and crop protection.
Used in Medicinal Chemistry Research:
2-(Isopropylsulfonyl)ethanamine also finds application in the field of medicinal chemistry, where it is used in the research and development of novel pharmaceutical compounds. Its reactivity and functional groups make it a promising candidate for the synthesis of new molecules with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 320337-16-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,0,3,3 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 320337-16:
(8*3)+(7*2)+(6*0)+(5*3)+(4*3)+(3*7)+(2*1)+(1*6)=94
94 % 10 = 4
So 320337-16-4 is a valid CAS Registry Number.
320337-16-4Relevant academic research and scientific papers
Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series
Petrov, Kimberly G.,Zhang, Yue-Mei,Carter, Malcolm,Cockerill, G. Stuart,Dickerson, Scott,Gauthier, Cassandra A.,Guo, Yu,Mook Jr., Robert A.,Rusnak, David W.,Walker, Ann L.,Wood, Edgar R.,Lackey, Karen E.
, p. 4686 - 4691 (2007/10/03)
Synthetic modifications on a 6-furanylquinazoline scaffold to optimize the dual ErbB-1/ErbB-2 tyrosine kinase inhibition afforded consistent SAR whereby a 4-(3-fluorobenzyloxy)-3-haloanilino provided the best enzyme potency and cellular selectivity. Changes made to the 6-furanyl group had little impact on the enzyme activity, but appeared to dramatically affect the cellular efficacy. The discovery of lapatinib emerged from this work.
Anilinoquinazolines as protein tyrosine kinase inhibitors
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Page/Page column 75, (2008/06/13)
Heteroaromatic compounds are described, methods for their preparation, pharmaceutical compositions containing them, methods of use, and their use in medicines. In particular, the invention relates to quinazoline and pyridopyrimidine derivatives which exhibit protein tyrosine kinase inhibition.
