320342-76-5Relevant articles and documents
Stereoselective synthesis of 8,9-licarinediols
Nascimento, Isabele R.,Lopes, Lucia M.X.,Davin, Laurence B.,Lewis, Norman G.
, p. 9181 - 9193 (2000)
The total synthesis of 8,9-licarinediols was selectively carried out from licarin A, previously obtained by oxidative coupling of (E)-isoeugenol. The corresponding enantiomerically pure (+)- and (-)-licarin A ester derivatives were subjected to Sharpless oxidation to yield the asymmetric C-8, C-9 dihydroxylation products, whose absolute configurations were established by means of the CD and NMR spectroscopic analyses of their Mosher ester derivatives. (C) 2000 Elsevier Science Ltd.