320350-04-7Relevant academic research and scientific papers
Synthesis and evaluation of pharmacological and pharmacokinetic properties of 11H-[1,2,4]triazolo[4,5-c][2,3]benzodiazepin-3(2H)-ones
Zappalà,Gitto,Bevacqua,Quartarone,Chimirri,Rizzo,De Sarro,De Sarro
, p. 4834 - 4839 (2000)
A series of 2,3-benzodiazepine derivatives has been previously described as noncompetitive AMPA-type glutamate receptor antagonists potentially useful for treatment of epilepsy. To further explore the structure-activity relationships of AMPA antagonists,
Design and development of 2,3-benzodiazepine (CFM) noncompetitive AMPA receptor antagonists
Gitto, Rosaria,Zappala, Maria,De Sarro, Giovambattista,Chimirri, Alba
, p. 129 - 134 (2007/10/03)
2,3-Benzodiazepines represent a class of heterocyclic compounds that interact with AMPA-type glutamate receptors in a noncompetitive manner. These compounds have attracted great interest for their pharmacological effects against acute and chronic neurodeg
