320365-81-9

Basic information

• Product Name: Quinazoline, 4-(4-bromo-2-fluorophenoxy)-6-methoxy-7-[(1-methyl-4-piperidinyl)meth oxy]-
• CAS NO: 320365-81-9
• Molecular Formula: C22H23BrFN3O3
• Molecular Weight: 476.345
• Mol File: 320365-81-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Quinazoline, 4-(4-bromo-2-fluorophenoxy)-6-methoxy-7-[(1-methyl-4-piperidinyl)meth oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinazoline, 4-(4-bromo-2-fluorophenoxy)-6-methoxy-7-[(1-methyl-4-piperidinyl)meth oxy]-(320365-81-9)
• EPA Substance Registry System: Quinazoline, 4-(4-bromo-2-fluorophenoxy)-6-methoxy-7-[(1-methyl-4-piperidinyl)meth oxy]-(320365-81-9)

Safety Data

• Hazardous Substances Data: 320365-81-9(Hazardous Substances Data)

Upstream product

• 2105-94-4 4-bromo-2-fluorophenol 
• 264208-72-2 4-chloro-6-methoxy-7-[(1'-methylpiperidin-4'-yl)methoxy]-quinazoline 

Relevant articles and documents

Quinazoline derivatives

The invention concerns quinazoline derivatives of Formula (I) wherein Q1includes a quinazoline ring optionally substituted with a group such as halogeno, trifluoromethyl and cyano, or a group of the formula: Q3—X1— wherein X1includes a direct bond and O and Q3includes aryl, aryl-(1-6C)alkyl, heterocyclyl and heterocyclyl-(1-6C)alkyl; each of R2and R3is hydrogen or (1-6C)alkyl; Z includes O, S and NH; and Q2includes aryl and aryl-(1-3C)alkyl or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of T cell mediated diseases or medical conditions in a warm-blooded animal.