32045-77-5

Upstream product

• 13565-39-4 3-(4-chlorophenyl)-1-p-tolylprop-2-en-1-one 

Downstream Products

• 131138-46-0 [3-(4-Chloro-phenyl)-5-hydroxy-5-p-tolyl-4,5-dihydro-pyrazol-1-yl]-phenyl-methanone 
• 131138-48-2 [3-(4-Chloro-phenyl)-5-hydroxy-5-p-tolyl-4,5-dihydro-pyrazol-1-yl]-(2-hydroxy-phenyl)-methanone 
• 131138-47-1 (4-Chloro-phenyl)-[3-(4-chloro-phenyl)-5-hydroxy-5-p-tolyl-4,5-dihydro-pyrazol-1-yl]-methanone 
• 131138-54-0 3-(4-chlorophenyl)-5-(4-methylphenyl)-1H-pyrazole 
• 1122500-35-9 C₂₄H₁₄Cl₃FN₄S 
• 13565-39-4 3-(4-chlorophenyl)-1-p-tolylprop-2-en-1-one 
• 1122500-66-6 (Z)-2-Bromo-3-(4-chloro-phenyl)-1-p-tolyl-propenone 
• 131138-49-3 1-[3-(4-Chloro-phenyl)-5-hydroxy-5-p-tolyl-4,5-dihydro-pyrazol-1-yl]-2-(naphthalen-2-yloxy)-ethanone 

Relevant academic research and scientific papers

A new synthetic strategy towards 2,4,5-trisubstituted 1H-imidazoles and highly substituted pyrrolo[1,2-c]imidazoles by use of α-azidochalcones via Michael addition-cyclization followed by Wittig reaction

Efficient and facile protocols for the preparation of highly functionalized 1H-imidazoles and 5H-pyrrolo[1,2-c]imidazoles are described. Heating a mixture of an α-azidochalcones and N,N,N′,N′-tetramethyl guanidine under neat conditions gave the corresponding 2,4,5-trisubstituted 1H-imidazole via Michael addition-cyclization in excellent yields. Subsequently, the prepared 1H-imidazoles undergo addition-Wittig reaction with acetylenic esters in presence of triphenylphosphine in dichloromethane to afford 5H-pyrrolo[1,2-c]imidazoles in high yields.

Analgesic and antimicrobial studies of some 2,4-dichloro-5-fluorophenyl containing arylidenetriazolothiadiazines

2,4-Dichloro-5-fluorophenyl containing 7-arylidenetriazolothiadiazines were obtained by the reaction of 4-amino-3-(2,4-dichloro-5-fluorophenyl)-5-mercapto- 1,2,4-triazole with 2,3-dibromo-1,3-diarylpropan-1-ones, and also by the reaction of 4-amino-3-(2,4