320739-93-3Relevant academic research and scientific papers
Participation of the conjugated diene part for potent cytotoxicity of callystatin A, a spongean polyketide
Murakami, Nobutoshi,Sugimoto, Masanori,Nakajima, Tatsuo,Kawanishi, Motoyuki,Tsutsui, Yasuhiro,Kobayashi, Motomasa
, p. 2651 - 2661 (2000)
5-epi, 10-epi, 8-Deethyl, and 10-demethyl analogues of callystatin A, a potent cytotoxic spongean polyketide, were synthesized to elucidate structure-requirement for cytotoxic potency. Inversion of the asymmetric center at C-10 in callystatin A minimally
