320742-96-9

Upstream product

• 106357-24-8 (3S,4S,5S)-6-(tert-butyldiphenylsiloxy)-4-hydroxy-3,5-dimethylhexan-1-ene 
• 320742-95-8 (2R,4R)-2,4-dimethyl-1-(tert-butyldiphenylsilyloxy)-5-hexene 

Downstream Products

• 247184-89-0 (-)-(3S,7S,8R,10R,2'S)-kalkitoxin 
• 320742-97-0 (2R,4R)-6-azido-2,4-dimethyl-1-(tert-butyldiphenylsilyloxy)hexane 
• 247184-89-0 (+)-(3R,7S,8R,10R,2'S)-kalkitoxin 
• 320743-01-9 (4S)-phenyl-3-[(4R,6R)-4,6-dimethyl-8-((2S)-N-methyl-2-methylbutyramido)-(E)-2-octenoyl]-2-oxazolidine 
• 320742-98-1 N-[6-(tert-butyl-diphenyl-silanyloxy)-3,5-dimethyl-hexyl]-2-methyl-butyramide 
• 320742-99-2 (2S)-N-methyl-N-[(3R,5R)-3,5-dimethyl-6-(tert-butyldiphenylsilyloxy)-hex-1-yl]-2-methylbutyramide 
• 320743-02-0 (4S)-phenyl-3-[(3S,4R,6R)-3,4,6-trimethyl-8-((2S)-N-methyl-2-methylbutyramido)-octanoyl]-2-oxazolidine 

Relevant academic research and scientific papers

An expeditious total synthesis of kalkitoxins: Determination of the absolute stereostructure of natural kalkitoxin

Kalkitoxin, a potent neurotoxin isolated from the marine cyanobacteria Lyngbya majuscula, and its congeners (1-7) were efficiently synthesized utilizing Hruby's diastereoselective 1,4-addition and the Wipf's oxazoline-thiazoline conversion as key steps. T

Stereoselective synthesis of syn- and anti-1,3- and 1,2-dimethyl arrays via asymmetric conjugate additions

Asymmetric conjugate additions have been investigated with enantiopure N-enoyloxazolidinones for efficient construction of syn and anti-1,3-dimethyl arrays on an acyclic carbon backbone. Reactions of Yamamoto organocopper species exhibit characteristics of double asymmetric induction resulting from influences of the 4-substituted chiral auxiliary and features of side chain stereochemistry.