320778-07-2Relevant academic research and scientific papers
An unusual enhancement of chiral induction by chiral 2-imidazolidinone auxiliaries
Abdel-Aziz,Okuno,Tanaka,Ishizuka,Matsunaga,Kunieda
, p. 8533 - 8537 (2007/10/03)
Diastereoselectivity which is induced by the use of 2-imidazolidinone auxiliaries is greatly dependent on the N-substituents of the heterocycles, among which the bulky arenesulfonyl group is the moiety of choice. Reactions of this type afford an excellent level of diastereoselection in the methylation of N'-butyryl-2-imidazolidinones via the metal enolates. (C) 2000 Published by Elsevier Science Ltd.
