32121-34-9Relevant academic research and scientific papers
Gold-catalyzed chemoselective formal (3+2)-Annulation reaction between β-naphthols and methyl aryldiazoacetate
Harada, Shingo,Sakai, Chigaya,Tanikawa, Koki,Nemoto, Tetsuhiro
, p. 3650 - 3656 (2019)
A chemoselective domino annulation reaction of β-naphthols with methyl aryldiazoacetate is described. The gold catalyst promoted C–H functionalization of β-naphthols, whereas a rhodium or copper complex led to O–H insertion reactions. Consecutive intramol
Photochemical O-H Functionalization of Aryldiazoacetates with Phenols via Proton Transfer
Empel, Claire,Jana, Sripati,Pei, Chao,Nguyen, Thanh Vinh,Koenigs, Rene M.
supporting information, p. 7225 - 7229 (2020/10/02)
In this work, we report a thorough investigation of the reaction of phenols with aryldiazoacetates. Mechanistic studies using different spectroscopic methods and theoretical calculations suggest a hydrogen bond between phenol and aryldiazoacetates, which can be modulated by the phenol acidity. The pKA of phenol and therefore the hydrogen bond plays an important role in a subsequent photoinduced proton transfer reaction to give the formal O-H functionalization product of phenols.
