32142-31-7Relevant academic research and scientific papers
Berchemolide, a novel dimeric vanillic acid glucoside from Berchemia racemosa
Sakurai,Kobayashi,Shigihara,Inoue
, p. 851 - 853 (1992)
A new phenol glycoside named berchemolide was isolated together with (+)-catechin and (-)-epicatechin (as acetates), from the stems of Berchemia racemosa SIEB. et ZUCC. (Rhamnaceae). The structure of berchemolide, having a dimeric dilactone structure with
Synthesis of eugenol-derived glucosides and evaluation of their ability in inhibiting the angiotensin converting enzyme
Alvarenga, Dalila Junqueira,Carvalho, Diogo Teixeira,Cordeiro, Cleydson Finotti,Dias, Danielle Ferreira,Matias, Laira Maria Faria,Souza, Thiago Belarmino de,Lavorato, Stefania Neiva,Pereira, Marília Gabriella Alves Goulart
, (2020/10/15)
We report here a series of glucosides which are active as inhibitors of the angiotensin converting enzyme (ACE). They are structurally related to the natural compound eugenol and exhibited significant inhibition values. Their syntheses were expeditious and we could obtain informative docking plots of them complexed to this enzyme. A glucoside derived from eugenol, carrying a carboxylic group in the aglycone, was the most active of them (with an IC50 of 0.4 mM) and showed good binding energies in docking studies with ACE. Moreover, computational prediction of toxicity risks, physicochemical properties and drug score show that the glucoside derivative of eugenol is a suitable compound for optimisation studies aimed at finding new drug candidates.
GLUCOSYRINGIC ACID ANALOGS AS SWEETNESS PROFILE MODIFIERS
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Paragraph 0241; 0243, (2018/04/02)
The present disclosure provides novel sweetener compositions comprising a compound having a structure according to Formula I: wherein R1, R2, R3, and R4 are described herein. Also provided are methods of modulating sweetness profile of a product by adding a compound of Formula I to the product, such as a beverage product or a food product. For example, the compound described herein can be added to increase the overall sweetness of a nutritive sweetener sweetened beverages; decrease the sweetness time-of-onset for high potency sweeteners such as rebaudioside A; decreasing bitter, metallic and licorice off-notes of high potency sweeteners; and improve the sweet quality of sweetened products.
