321435-40-9

Upstream product

• 321435-38-5 (R)-3-((2S,4R)-4-Benzyl-5-oxo-tetrahydro-furan-2-carbonyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid allyl ester 
• 74788-82-2 (2,6-dimethylphenyl)methanamine 
• 321435-39-6 (R)-3-((2S,4R)-4-Benzyl-5-oxo-tetrahydro-furan-2-carbonyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid 
• 321435-37-4 5,5-dimethyl-thiazolidine-3,4-dicarboxylic acid 4-allyl ester 3-tert-butyl ester 
• 588729-32-2 (2S,4R)-4-Benzyl-5-oxo-tetrahydro-furan-2-carboxylic acid 
• 588729-47-9 (R)-5,5-Dimethyl-thiazolidine-4-carboxylic acid allyl ester 
• 72778-00-8 (R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid 
• 117918-23-7 (R)-3-tert-butoxycarbonyl-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid 
• 150407-67-3 dihydro-5(S)-(hydroxymethyl)-3(R)-(phenylmethyl)-3(2H)-furanone 

Downstream Products

• 321435-42-1 (R)-3-[(2S,4R)-2-(tert-Butyl-dimethyl-silanyloxy)-4-((3S,4S)-3-hydroxy-chroman-4-ylcarbamoyl)-5-phenyl-pentanoyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,6-dimethyl-benzylamide 
• 321435-41-0 (2R,4S)-2-Benzyl-4-(tert-butyl-dimethyl-silanyloxy)-5-[(R)-4-(2,6-dimethyl-benzylcarbamoyl)-5,5-dimethyl-thiazolidin-3-yl]-5-oxo-pentanoic acid 

Relevant academic research and scientific papers

Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus

A series of highly potent HIV protease inhibitors have been designed and synthesized. These compounds are active against various clinical viral isolates as well as wild-type virus. The synthesis and biological activity of these HIV protease inhibitors are discussed.