321435-43-2Relevant articles and documents
Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus
Lu, Zhijian,Raghavan, Subharekha,Bohn, Joann,Charest, Mark,Stahlhut, Mark W.,Rutkowski, Carrie A.,Simcoe, Amy L.,Olsen, David B.,Schleif, William A.,Carella, Anthony,Gabryelski, Lori,Jin, Lixia,Lin, Jiunn H.,Emini, Emilio,Chapman, Kevin,Tata, James R.
, p. 1821 - 1824 (2007/10/03)
A series of highly potent HIV protease inhibitors have been designed and synthesized. These compounds are active against various clinical viral isolates as well as wild-type virus. The synthesis and biological activity of these HIV protease inhibitors are discussed.