32149-09-0

Basic information

• Product Name: trans-2-Methyl-4-chromanol
• Synonyms: trans-2-Methyl-4-chromanol
• CAS NO: 32149-09-0
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 32149-09-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: trans-2-Methyl-4-chromanol(CAS DataBase Reference)
• NIST Chemistry Reference: trans-2-Methyl-4-chromanol(32149-09-0)
• EPA Substance Registry System: trans-2-Methyl-4-chromanol(32149-09-0)

Safety Data

• Hazardous Substances Data: 32149-09-0(Hazardous Substances Data)

Upstream product

• 5751-48-4 2-methylchromone 

Relevant articles and documents

Synthesis of chiral chromanols: Via a RuPHOX-Ru catalyzed asymmetric hydrogenation of chromones

Chiral chromanols and their derivatives have been synthesized via a RuPHOX-Ru catalyzed asymmetric hydrogenation of chromones in high yields, >20:1 drs and with up to 99.9% ee. Control experiments show that the reaction undergoes two sequential asymmetric hydrogenation steps of the CC and CO double bonds. The reaction could be performed on a gram-scale with a relatively low catalyst loading (up to 1000 S/C), and the resulting products can be transformed to several biologically active compounds.