32149-57-8

Basic information

• Product Name: Magnesium tert-butoxide
• Synonyms: MagnesiuM tert-butoxide, 90+%;Magnesium Tertiary Butoxide;Magnesium tert-butoxide, technical, 90%;MTB;MAGNESIUM TERT-BUTOXIDE;MAGNESIUM DI-TERT-BUTOXIDE;magnesium 2-methylpropan-2-olate;Magnesiumtert-butoxide,94%
• CAS NO: 32149-57-8
• Molecular Formula: 2C₄H₉O*Mg
• Molecular Weight: 170.53
• EINECS: 250-931-3
• Product Categories: Materials Science;Metal and Ceramic Science;Organic Bases;Salts;Synthetic Reagents;Chemical Synthesis;Magnesium Salts
• Mol File: 32149-57-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 84.6 °C at 760 mmHg
• Flash Point: 11.7 °C
• Appearance: White to light gray/Powder
• Vapor Pressure: 46mmHg at 25°C
• Storage Temp.: Flammables area
• Water Solubility: Reacts with water.
• Sensitive: Air & Moisture Sensitive
• BRN: 3979348
• CAS DataBase Reference: Magnesium tert-butoxide(CAS DataBase Reference)
• NIST Chemistry Reference: Magnesium tert-butoxide(32149-57-8)
• EPA Substance Registry System: Magnesium tert-butoxide(32149-57-8)

Safety Data

• Hazard Codes: F,C
• Statements: 11-14-34
• Safety Statements: 26-36/37/39-43-45
• RIDADR: UN 2921 8/PG 2
• WGK Germany: 3
• F: 10-21
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 32149-57-8(Hazardous Substances Data)

Usage

Uses

Magnesium tert-butoxide is used as a pharmaceutical intermediate. It is also used in deprotonation reactions for organic syntheses.

InChI:InChI=1/C4H9O.Mg/c1-4(2,3)5;/h1-3H3;/q-1;+2

Synthetic route

(Ra)-4-hydroxy-2,6-diphenyldinaphtho[1,3,2]dioxaphosphepine 4-oxide + magnesium 2-methylpropan-2-olate (32149-57-8) → C64H40MgO8P2

Conditions	Yield
In methanol; dichloromethane at 20℃; for 0.5h; Inert atmosphere;	100%

vortioxetine (508233-74-7) + magnesium 2-methylpropan-2-olate (32149-57-8) + {[(4-methylbenzenesulfonyl)oxy]methyl}phosphonic acid (161760-09-4) → C23H33N2O3PS

Conditions	Yield
Stage #1: vortioxetine; magnesium 2-methylpropan-2-olate In N,N-dimethyl-formamide at 60℃; for 0.333333h; Stage #2: {[(4-methylbenzenesulfonyl)oxy]methyl}phosphonic acid In N,N-dimethyl-formamide at 60 - 70℃; for 6h;	84.5%

[Sn(OBu(t))(μ-OBu(t))]2 + magnesium 2-methylpropan-2-olate (32149-57-8) → Mg bis(tri-tert-butoxistannate(II))

Conditions	Yield
In benzene boiling in benzene; 1H-NMR;	0%

(R)-(-)-2,2'-diphenyl-4-biphenanthrol hydrogen phosphate + magnesium 2-methylpropan-2-olate (32149-57-8) → magnesium(II) (R)-2,2'-diphenyl-3,3'-biphenanthryl-4,4'-diyl phosphate

Conditions	Yield
In methanol; dichloromethane at 20℃; for 0.5h;

triethylsilane (617-86-7) + magnesium 2-methylpropan-2-olate (32149-57-8) → 2C10H25OSi(1-)*Mg(2+)

Conditions	Yield
In tetrahydrofuran at 45℃; for 36h;

(R)-3,3'-bis(9-anthracenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate + magnesium 2-methylpropan-2-olate (32149-57-8) → 2C48H28O4P(1-)*Mg(2+)

Conditions	Yield
In methanol; dichloromethane at 20℃; for 1h; Inert atmosphere;

(R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid + magnesium 2-methylpropan-2-olate (32149-57-8) → 2C50H56O4P(1-)*Mg(2+)

Conditions	Yield
In methanol; dichloromethane at 20℃; for 1h; Inert atmosphere;

C53H43O4PSi2 + magnesium 2-methylpropan-2-olate (32149-57-8) → 2C53H42O4PSi2(1-)*Mg(2+)

Conditions	Yield
In methanol; dichloromethane at 20℃; for 0.5h; Schlenk technique;