3215-24-5

Usage

Uses

Used in Neuroscience Research:
(8xi,12xi)-2-aminostrychnidin-10-one is used as a chemical tool for studying [application reason] in the central nervous system. It aids in understanding the mechanisms of receptors and synaptic transmission, which are crucial for neurological functions.
Used in Pharmaceutical Development:
(8xi,12xi)-2-aminostrychnidin-10-one is used as a compound in the development of [application type] for [application reason]. Its neurotoxic properties may be harnessed for the creation of drugs targeting specific neurological conditions, provided that its safety and efficacy are thoroughly evaluated.
Used in Toxicology Studies:
(8xi,12xi)-2-aminostrychnidin-10-one is used as a reference compound in [application type] for [application reason]. Its structural similarity to strychnine and its convulsant properties make it a valuable tool for studying the effects of neurotoxic substances on the body.

Upstream product

• 66-32-0 strychnine nitrate 
• 29854-52-2 10-Nitrostrychnine 

Downstream Products

• 509-36-4 β-colubrine 
• 58523-41-4 (4aR,4a1R,5aS,8aR,8a1S,15aS)-10-bromo-2,4a,4a1,5,5a,7,8,8a1,15,15a-decahydro-14H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one 
• 19894-24-7 10-hydroxystrychnine 
• 58523-48-1 2-Acetamido-strychnin 

Relevant academic research and scientific papers

Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists

A series of (E)-11-isonitrosostrychnine oxime ethers, 2-aminostrychnine, (strychnine-2-yl)propionamide, 18-oxostrychnine, and N-propylstrychnine bromide were synthesized and evaluated pharmacologically at human α1 and α1β glycine receptors in a functional

Silver-catalyzed late-stage fluorination

Carbon-fluorine bond formation by transition metal catalysis is difficult, and only a few methods for the synthesis of aryl fluorides have been developed. All reported transition-metal-catalyzed fluorination reactions for the synthesis of functionalized arenes are based on palladium. Here we present silver catalysis for carbon-fluorine bond formation. Our report is the first example of the use of the transition metal silver to form carbon-heteroatom bonds by cross-coupling catalysis. The functional group tolerance and substrate scope presented here have not been demonstrated for any other fluorination reaction to date.