321558-46-7Relevant academic research and scientific papers
Knoevenagel reaction of diethylphosphonoacetic acid: A facile route to diethyl (E)-2-arylvinylphosphonates
Krawczyk, Henryk,Albrecht, Lukasz
, p. 2887 - 2896 (2007/10/03)
Knoevenagel reaction of aromatic aldehydes or α-substituted aliphatic aldehydes with diethylphosphonoacetic acid leads to the formation of 3-substituted-2-(diethoxyphosphoryl)acrylic acids. Decarboxylation of the resulting (E)-3-aryl-2-(diethoxyphosphoryl)acrylic acids afforded diethyl (E)-2-arylvinylphosphonates. Direct synthesis of diethyl vinylphosphonates from some aromatic aldehydes and formaldehyde is also reported. Georg Thieme Verlag Stuttgart.
Design, synthesis, and evaluation of pharmacological properties of cinnamic derivatives as antiatherogenic agents
Lapeyre, Caroline,Delomenède, Mélanie,Bedos-Belval, Florence,Duran, Hubert,Nègre-Salvayre, Anne,Baltas, Michel
, p. 8115 - 8124 (2007/10/03)
A series of cinnamic and phosphonocinnamic derivatives have been synthesized and their ability to inhibit cell-mediated LDL oxidation and oxidized LDL-induced cytotoxicity was investigated. Electron-donating substituents surrounding the necessary 4-OH gro
