321582-01-8

Upstream product

• 4925-88-6 2,5-dimethoxy-4-methylbenzaldehyde 
• 321581-98-0 3-(2,5-dimethoxy-4-methyl-phenyl)-prop-2-yn-1-ol 
• 321581-99-1 3-(2,5-dimethoxy-4-methylphenyl)-2E-propenol 
• 75056-76-7 1-iodo-2,5-dimethoxy-4-methylbenzene 
• 321582-00-7 1-(2,5-dimethoxy-4-methylphenyl)-3-(ethenyloxy)-1E-propene 

Downstream Products

• 321582-03-0 3-(2,5-dimethoxy-4-methylphenyl)pentamethylene diacetate 
• 321582-19-8 (3S)-5-hydroxy-3-(2,5-dimethoxy-4-methylphenyl)pentyl acetate 
• 321582-02-9 3-(2,5-dimethoxy-4-methylphenyl)pentane-1,5-diol 

Relevant academic research and scientific papers

Enantioselective Iridium-Catalyzed α-Allylation with Aqueous Solutions of Acetaldehyde

The enantioselective α-allylation of aqueous solutions of acetaldehyde using iridium- A nd amine-catalyzed substitution of racemic allylic alcohols is described. The method utilizes a readily available, safely handled aqueous solution of acetaldehyde and furnishes ?,?-unsaturated aldehydes in good yields and greater than 99% enantiomeric excess. The synthetic potential of the method is demonstrated with the enantioselective formal syntheses of heliannuols C and E as well as heliespirones A and C.