32162-64-4 Usage
Uses
Used in Research and Development:
R-(+)-COTININE is used as a research compound for studying its properties and potential applications in various fields. As a metabolite of Nicotine, it can be utilized in the development of new drugs or therapies targeting nicotine addiction or related health issues.
Used in Pharmaceutical Industry:
R-(+)-COTININE is used as a reference compound in the pharmaceutical industry for quality control and standardization of Nicotine and Cotinine measurements. This helps in ensuring the accuracy and reliability of diagnostic tests and treatments involving these substances.
Used in Toxicology Studies:
R-(+)-COTININE is used as a toxicological reference in toxicology studies, particularly in understanding the effects of Nicotine and its metabolites on human health. This information can be crucial in developing strategies to mitigate the harmful effects of tobacco use and exposure to secondhand smoke.
Used in Environmental Monitoring:
R-(+)-COTININE can be used as a marker in environmental monitoring to detect the presence of Nicotine and its metabolites in various ecosystems. This can help in assessing the impact of tobacco use on the environment and developing measures to reduce contamination.
Used in Analytical Chemistry:
R-(+)-COTININE is used as a reference material in analytical chemistry for the development and validation of analytical methods and techniques for detecting and quantifying Nicotine and its metabolites in various samples, such as biological fluids, tissues, and environmental matrices.
Check Digit Verification of cas no
The CAS Registry Mumber 32162-64-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,1,6 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 32162-64:
(7*3)+(6*2)+(5*1)+(4*6)+(3*2)+(2*6)+(1*4)=84
84 % 10 = 4
So 32162-64-4 is a valid CAS Registry Number.
32162-64-4Relevant academic research and scientific papers
Evaluation of the Edman degradation product of vancomycin bonded to core-shell particles as a new HPLC chiral stationary phase
Hellinghausen, Garrett,Lopez, Diego A.,Lee, Jauh T.,Wang, Yadi,Weatherly, Choyce A.,Portillo, Abiud E.,Berthod, Alain,Armstrong, Daniel W.
, p. 1067 - 1078 (2018/08/01)
A modified macrocyclic glycopeptide-based chiral stationary phase (CSP), prepared via Edman degradation of vancomycin, was evaluated as a chiral selector for the first time. Its applicability was compared with other macrocyclic glycopeptide-based CSPs: TeicoShell and VancoShell. In addition, another modified macrocyclic glycopeptide-based CSP, NicoShell, was further examined. Initial evaluation was focused on the complementary behavior with these glycopeptides. A screening procedure was used based on previous work for the enantiomeric separation of 50 chiral compounds including amino acids, pesticides, stimulants, and a variety of pharmaceuticals. Fast and efficient chiral separations resulted by using superficially porous (core-shell) particle supports. Overall, the vancomycin Edman degradation product (EDP) resembled TeicoShell with high enantioselectivity for acidic compounds in the polar ionic mode. The simultaneous enantiomeric separation of 5 racemic profens using liquid chromatography-mass spectrometry with EDP was performed in approximately 3?minutes. Other highlights include simultaneous liquid chromatography separations of rac-amphetamine and rac-methamphetamine with VancoShell, rac-pseudoephedrine and rac-ephedrine with NicoShell, and rac-dichlorprop and rac-haloxyfop with TeicoShell.
Kinetic resolution in the oxidation of iminium ion to lactam catalysed by aldehyde oxidase.
Bielawski,Brand?nge,Rodriguez
, p. 198 - 201 (2007/10/02)
A rabbit liver enzyme preparation oxidised racemic iminium ions 1 and 2 to optically active lactams 3 and 4 with enantiomer ratios ER/S = 5.5 and 0.14, respectively.
