321745-86-2

Usage

Uses

Used in Pharmaceutical Industry:
2-TERT-BUTOXY-2-OXOETHYLZINC CHLORIDE is used as a reagent for organic synthesis, specifically in the formation of carbon-carbon bonds through cross-coupling reactions. Its efficiency and versatility make it a valuable tool in the development of new pharmaceutical compounds.
Used in Agrochemical Industry:
In the agrochemical industry, 2-TERT-BUTOXY-2-OXOETHYLZINC CHLORIDE is used as a reagent for organic synthesis to create new agrochemical compounds. Its ability to form carbon-carbon bonds through cross-coupling reactions contributes to the development of innovative products in this field.
Used in Carbon-Carbon Bond Formation:
2-TERT-BUTOXY-2-OXOETHYLZINC CHLORIDE is used as an activator for carbon dioxide in carbon-carbon bond formation reactions. This capability expands the range of reactions and products that can be synthesized, offering new possibilities in organic chemistry.

InChI:InChI=1/C6H11O2.ClH.Zn/c1-5(7)8-6(2,3)4;;/h1H2,2-4H3;1H;/q;;+1/p-1/rC6H11ClO2Zn/c1-6(2,3)9-5(8)4-10-7/h4H2,1-3H3

Upstream product

• 540-88-5 acetic acid tert-butyl ester 

Downstream Products

• 1007571-82-5 C₂₀H₁₇ClF₃NO₃ 
• 1086282-12-3 tert-butyl {2-[(1-biphenyl-4-yl-2-oxo-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)methyl]pyridin-3-yl}acetate 
• 1169483-80-0 tert-butyl 2-(4-(4-(tert-butylcarbamoyl)-2-nitro-phenoxy)-5-chloro-2-fluorophenyl)acetate 
• 1240523-88-9 tert-butyl 2-(3-chloro-5-nitrophenyl)acetate 
• 1240523-89-0 tert-butyl 2-(3-nitro-5-(pyridin-4-yl)phenyl)acetate 
• 1588944-96-0 benzyl 4-((1R,2S)-2-((4-(2-tert-butoxy-2-oxoethyl)-2-fluorobenzyloxy)methyl)cyclopropyl)piperidine-1-carboxylate 
• 1616596-28-1 tert-butyl (4-amino-2,6-difluorophenyl)acetate 
• 1616596-33-8 tert-butyl 2-(2-cyano-4-(1H-tetrazol-1-yl)phenyl)acetate 
• 1616596-29-2 tert-butyl [2,6-difluoro-4-(1H-tetrazol-1-yl)phenyl]acetate 
• 601513-27-3 2-chloro-4-(trifluoromethyl)phenylacetic acid tert-butyl-ester 
• 1420069-11-9 tert-butyl {1-[2-{[(cyclopropylcarbonyl)(ethyl)amino]methyl}-4-(trifluoromethyl)phenyl]-6-fluoro-1H-indol-3-yl}acetate 
• 1420070-71-8 tert-butyl 2-(1-(2-((N-ethylcyclopropanecarboxamido)methyl)-4-(trifluoromethyl)phenyl)-6-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetate 
• 1420070-67-2 tert-butyl {1-[2-{[(cyclopropylcarbonyl)(ethyl)amino]methyl}-4-(trifluoromethyl)phenyl]-6-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl}acetate 
• 1420070-48-9 tert-butyl {1-[2-{[(cyclopropylcarbonyl)(ethyl)amino]methyl}-4-(trifluoromethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}acetate 

Relevant academic research and scientific papers

Alkenylation of C(sp3)?H Bonds by Zincation/Copper-Catalyzed Cross-Coupling with Iodonium Salts

α-Vinylation of phosphonates, phosphine oxides, sulfones, sulfonamides, and sulfoxides has been achieved by selective C?H zincation and copper-catalyzed C(sp3)?C(sp2) cross-coupling reaction using vinylphenyliodonium salts. The vinylation transformation proceeds in high efficiency and stereospecificity under mild reaction conditions. This zincative cross-coupling reaction represents a general alkenylation strategy, which is also applicable for α-alkenylation of esters, amides, and nitriles in the synthesis of β,γ-unsaturated carbonyl compounds.