32178-92-0Relevant academic research and scientific papers
DESULPHURISATION OF PENICILLINS WITH TRIPHENYLSTANNANE
Baldwin, Jack E.,Adlington, Robert M.,Kang, Tae Won,King, Lionel G.,Patel, Vipulkumar K.
, p. 759 - 766 (2007/10/02)
Reaction of penicillins (and a cephalosporin) with triphenylstannane provide a novel and efficient route to dethioazetidinones.A study on the mechanism of this process is described.
The Ring Expasion of Penams to Cephams: a Possible Biomimetic Process
Baldwin, Jack E.,Adlington, Robert M.,Kang, Tae Won,Lee, Eun,Schofield, Christopher J.
, p. 5953 - 5958 (2007/10/02)
Reaction of a 2β-bromomethyl penam with triphenyltin hydride gave, via ring expansion of the derived 2β-methyl radical, the corresponding cepham system; a similar process may be in operation during the biosynthetic ring expansion of penicillin N to deacet
Ring Expansion of Penams to Cephams: a Possible Biomimetic Process
Baldwin, Jack E.,Adlington, Robert M.,Kang, Tae Won,Lee, Eun,Schofield, Christopher J.
, p. 104 - 106 (2007/10/02)
Homolytic reductive debromination of a 2β-bromomethyl penam by triphenyltin hydride provides, via ring expansion of the derived 2β-methyl radical, the corresponding cepham system; a similar process may explain the biosynthetic ring expansion of penicillin
