321855-40-7

Upstream product

• 115-19-5 2-methyl-but-3-yn-2-ol 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 1342341-12-1 C₂₄H₃₅NO₅S 
• 1342340-63-9 (1R)-1-cyclohexyl-9-(2-hydroxypropan-2-yl)-2-(4-methylphenylsulfonyl)-2,3-dihydro-1H-benzo[f]isoindole 
• 1342340-83-3 C₂₈H₃₅NO₃S 
• 1342341-13-2 N-[(1R)-1-cyclohexyl-4-hydroxy-4-methylpent-2-ynyl]-4-methylbenzenesulfonamide 
• 1342340-84-4 N-[(Z)-2-bromo-3-phenylprop-2-enyl]-N-[(1R)-1-cyclohexyl-4-hydroxy-4-methylpent-2-ynyl]-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

Palladium-catalyzed construction of polycyclic heterocycles by an alkyne insertion and direct arylation cascade

Cascade cyclization of bromoenynes bearing an aryl group with catalytic amounts of palladium(II) acetate and cesium carbonate led to the direct construction of tri- or tetracyclic heterocycles. Direct arylation of a pyrrole, furan or thiophene ring in the

Ligand accelerated indium(III)-catalyzed asymmetric alkynylation of aldehydes with 2-methyl-3-butyn-2-ol as an ethyne equivalent donor

Indium(III)-catalyzed asymmetric alkynylation of aryl, heteroaryl, alkyl and alkenyl aldehydes with 2-methyl-3-butyn-2-ol as an ethyne equivalent donor was realized, and products were obtained in moderate to good yields (up to 97%) and high enantioselecti

Enantioselective addition of 2-methyl-3-butyn-2-ol to aldehydes: Preparation of 3-hydroxy-1-butynes

(equation presented) We report the first example of enantioselective aldehyde additions of 2-methyl-3-butyn-2-ol, a commodity bulk chemical that is readily available. Following a facile fragmentation reaction, the addition reactions provide access to opti