321887-26-7

Upstream product

• 104-94-9 4-methoxy-aniline 
• 2579-22-8 Phenylpropargyl aldehyde 
• 106318-93-8 phenylpropargylidene p-anisidine 
• 173095-49-3 (3S,4R,5S)-4-ethoxycarbonyl-3-hydroxy-1-(4-methoxyphenyl)-5-phenylpropargyl-2-pyrrolidinone 

Downstream Products

• 321887-30-3 (3S,4S,5R)-3-benzyloxy-4-benzyloxymethyl-1-(4-methoxyphenyl)-5-[(Z)-2-phenylethenyl]-2-pyrrolidinone 
• 321887-35-8 (3S,4S,5R)-1-allyl-3-benzyloxy-4-benzyloxymethyl-5-(2-phenylethenyl)-2-pyrrolidinone 
• 321887-33-6 (3S,4S,5R)-3-benzyloxy-4-benzyloxymethyl-5-(2-phenylethenyl)-2-pyrrolidinone 
• 321887-45-0 (1S,2S,7S,7aS)-2-benzyloxy-1-benzyloxymethyl-7-hydroxy-7a-pyrrolizidine 
• 321887-42-7 (1aS,5S,6S,6aS,6bR)-5-benzyloxy-6-benzyloxymethylperhydrooxireno[2,3-a]pyrrolizin-4-one 
• 321887-37-0 (1S,2S,7aR)-2-benzyloxy-1-benzyloxymethyl-2,5,7a-trihydropyrrolizin-3-one 
• 321887-52-9 (1S,2S,7R,7aS)-2-benzyloxy-1-benzyloxymethyl-7-hydroxy-7a-pyrrolizidine 
• 321887-28-9 (3S,4S,5S)-3-benzyloxy-4-benzyloxymethyl-1-(4-methoxyphenyl)-5-phenylpropargyl-2-pyrrolidinone 

Relevant academic research and scientific papers

Stereoselectivity in the Condensation Reactions between Malate Enolate and Imines to 2-Pyrrolidinone Derivatives

Enolate dianion of diethyl (S)-malate was stereoselectively condensed with nonenolizable N-arylimines to give 2-pyrrolidinone derivatives.The presence of HMPA changes the diastereoselectivity of this cyclization reaction.