321903-46-2Relevant academic research and scientific papers
Tributyltin hydride-mediated radical cyclisation of aldehydes and unsaturated ketones: The synthesis of hydroxy tetrahydrofurans, chromanols and related compounds
Bebbington, David,Bentley, Jon,Nilsson, Paul A.,Parsons, Andrew F.
, p. 8941 - 8945 (2000)
The tributyltin hydride-mediated cyclisation of unsaturated ethers bearing an aldehyde or α,β-unsaturated ketone group is reported. Cyclisation proceeds via addition of the tributyltin radical to the carbonyl double bond and the resultant O-stannyl ketyl can add intramolecularly to electron-rich double bonds to form hydroxy tetrahydrofurans, chromanols or related compounds. (C) 2000 Elsevier Science Ltd.
