321995-62-4 Usage
Uses
Used in Pharmaceutical Research and Development:
2,6-difluoro-4-[(3-hydroxy-5,5,8,8,tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)-amino]-benzoic Acid is used as a research compound for the development of new pharmaceuticals. Its unique structure and functional groups may offer potential therapeutic properties, although further research is required to fully understand its applications and efficacy.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2,6-difluoro-4-[(3-hydroxy-5,5,8,8,tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)-amino]-benzoic Acid is used as a building block or intermediate in the synthesis of more complex molecules with potential medicinal properties. Its structural features may contribute to the development of novel drugs with improved pharmacokinetics, selectivity, and therapeutic effects.
Used in Drug Design and Optimization:
2,6-difluoro-4-[(3-hydroxy-5,5,8,8,tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)-amino]-benzoic Acid is employed in drug design and optimization processes to explore its potential as a lead compound or to modify its structure to enhance its pharmacological properties. Its unique features may provide insights into the design of new drugs with improved efficacy, safety, and selectivity.
Used in Biochemical and Pharmacological Studies:
In biochemical and pharmacological research, 2,6-difluoro-4-[(3-hydroxy-5,5,8,8,tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)-amino]-benzoic Acid is used as a tool compound to investigate its interactions with biological targets, such as enzymes, receptors, or ion channels. This information can help researchers understand its mechanism of action and potential therapeutic applications.
Used in Drug Discovery:
2,6-difluoro-4-[(3-hydroxy-5,5,8,8,tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)-amino]-benzoic Acid is utilized in drug discovery efforts to identify new therapeutic agents with novel mechanisms of action. Its unique chemical structure may provide a starting point for the development of innovative drugs to treat various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 321995-62-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,1,9,9 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 321995-62:
(8*3)+(7*2)+(6*1)+(5*9)+(4*9)+(3*5)+(2*6)+(1*2)=154
154 % 10 = 4
So 321995-62-4 is a valid CAS Registry Number.
321995-62-4Relevant academic research and scientific papers
Treatment of tumors with RARα selective retinoid compounds in combination with other anti-tumor agents
-
, (2008/06/13)
Compounds which are specific or selective agonists of RARα receptors in preference over RARβ and RARγ receptors, and particularly compounds of the formula where R is a H, lower alkyl of 1 to 6 carbons, or a pharmaceutically acceptable salt, are useful for
Synthesis and biological activity of retinoic acid receptor-α specific amides
Beard, Richard L.,Duong, Tien T.,Teng, Min,Klein, Elliott S.,Standevan, Andrew M.,Chandraratna, Roshantha A.S.
, p. 3145 - 3148 (2007/10/03)
Retinoids are analogues of all-trans-retinoic acid, a powerful hormone that mediates many fundamental biological processes. Cancer and other serious hyperproliferative diseases are attractive therapeutic targets for retinoids, but the therapeutic use of retinoids is limited due to severe toxicity. We report here the design of retinoid receptor-α specific ligands with growth inhibitory activity in breast cancer cell lines, and which do not cause the cutaneous toxicity associated with the currently available nonselective retinoid agonists.
Treatment of tumors with RARalpha selective retinoid compounds in combination with other anti-tumor agents
-
, (2008/06/13)
Compounds which are specific or selective agonists of RARα receptors in preference over RARβ and RARγ receptors, and particularly compounds of the formula where R is a H, lower alkyl of 1 to 6 carbons, or a pharmaceutically acceptable salt, are useful for