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3,4-dehydroproline, also known as 3,4-DHPro, is a non-proteinogenic amino acid derived from proline through the enzymatic oxidation process by proline 4-hydroxylase. It is a unique chemical entity that is integral to the structure of various bioactive peptides, including those with antifungal and antifouling properties. Characterized by its capacity to disrupt the formation of secondary structures in proteins, 3,4-DHPro holds promise as a therapeutic agent and is a subject of interest in drug development, chemical synthesis, and drug design due to its distinctive chemical properties.

3220-74-4

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3220-74-4 Usage

Uses

Used in Pharmaceutical Development:
3,4-dehydroproline is utilized as a key component in the development of pharmaceuticals, particularly for its potential therapeutic applications. Its ability to interfere with protein secondary structures makes it a candidate for targeting protein misfolding diseases and other conditions where protein structure plays a critical role.
Used in Chemical Synthesis:
In the field of chemical synthesis, 3,4-dehydroproline serves as a valuable intermediate or building block for the creation of complex organic compounds. Its unique structure allows for the synthesis of novel molecules with potential applications in various industries.
Used in Drug Design:
3,4-dehydroproline is employed as a structural element in drug design, where its properties can be leveraged to enhance the efficacy and selectivity of drug molecules. Its role in disrupting protein structures can be particularly useful in designing drugs that target specific protein conformations associated with diseases.
Used in Bioactive Peptide Research:
In the research of bioactive peptides, 3,4-dehydroproline is used as a constituent in the development of compounds with antifungal and antifouling capabilities. Its presence in these peptides contributes to their biological activities, making it an important component in the discovery and optimization of new bioactive agents.
Used in Protein Structure Studies:
3,4-dehydroproline is applied in the study of protein structures to understand the effects of non-canonical amino acids on protein folding and stability. This knowledge can be instrumental in the development of new therapeutic strategies targeting protein misfolding and related diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 3220-74-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,2,2 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3220-74:
(6*3)+(5*2)+(4*2)+(3*0)+(2*7)+(1*4)=54
54 % 10 = 4
So 3220-74-4 is a valid CAS Registry Number.

3220-74-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Proline, 3,4-didehydro-

1.2 Other means of identification

Product number -
Other names 1H-Pyrrole-2-carboxylic acid,2,5-dihydro-(9ci)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3220-74-4 SDS

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