32223-67-9

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 39905-50-5 4-pentyloxyaniline 
• 15872-41-0 4-(pentyloxy)benzoic acid 

Downstream Products

• 1422194-31-7 2-hydroxy-1-oxo-N-(4-(pentyloxy)phenyl)-2,3-dihydro-1H-indene-2-carboxamide 
• 1422194-16-8 C₂₁H₂₃NO₃ 
• 26613-36-5 (4-Pentyloxy-phenyl)-carbamic acid (1S,2S)-2-pyrrolidin-1-yl-cyclohexyl ester; hydrochloride 
• 112922-97-1 (4-Pentyloxy-phenyl)-carbamic acid 2-morpholin-4-yl-ethyl ester; hydrochloride 

Relevant academic research and scientific papers

Oxime Carbamate-Discovery of a series of novel FAAH inhibitors

A series of novel oxime carbamates have been identified as potent inhibitors of the key regulatory enzyme of the endocannabinoid signaling system, fatty acid amide hydrolase (FAAH). In this Letter, the rationale behind the discovery and the biological evaluations of this novel class of FAAH inhibitors are presented. Both in vitro and in vivo results of selected targets are discussed, along with inhibition kinetics and molecular modeling studies.1.

Comparison of base-promoted and self-catalyzed conditions in the synthesis of isocyanates from amines using triphosgene

Comparison of base-promoted and self-catalyzed conditions for the synthesis of isocyanates from amines and triphosgene shows no advantage in using an amine base in the majority of cases. The workup and isolation of the product is simplified under base-free conditions. Yields of between 50 and 90% after distillation were common. Only acid-sensitive substrates need a base catalyst. Copyright Taylor & Francis Group, LLC.

Quantitative Structure-Activity Relationships of Insecticidal Pyrazolines

Methyl 3-(4-chlorophenyl)-4-methyl-1--2-pyrazoline-4-carboxylates and related compounds were prepared. Their convulsant activity was determined as the minimum dose required to bring about the symptom within 1 h after injection against male adult American cockroaches, Periplaneta americana (L.). Insecticidal activity with metabolic inhibitors for oxidation and hydrolysis was measured 24 h after injection of the test compounds. Variations in each of the activities were analysed by using physicochemical substituent parameters and regression analysis. The findings indicated that the greater the hydrophobicity and the more the electron-withdrawing property of the substituents, the higher were the activities. Variations in each of the two activities were parabolically related to the STERIMOL width parameter with an optimum value of about zero.