32224-57-0

Usage

Uses

Used in Pharmaceutical Industry:
Heptanedioic acid, 2-amino-, (2R)is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex organic compounds, contributing to the development of new drugs and therapeutic agents.
Used in Biochemical Research:
In the field of biochemical research, Heptanedioic acid, 2-amino-, (2R)is utilized for studying the biosynthesis of essential amino acids like lysine, providing insights into metabolic pathways and potential targets for medical interventions.
Used in Organic Synthesis:
Heptanedioic acid, 2-amino-, (2R)is employed as a building block in organic synthesis, enabling the creation of a wide range of organic compounds for various applications, including specialty chemicals and materials.
Used in Chiral Chemistry:
As a chiral molecule, Heptanedioic acid, 2-amino-, (2R)is used in chiral chemistry to explore the properties and applications of enantiomers, which can have different biological activities and may be crucial in the development of enantioselective synthesis methods and enantiomerically pure compounds.

Upstream product

• 156387-02-9 (2RS)-α-Ethyl ω-methyl 2-(N-acetylamino)pimelate 
• 88425-36-9 (S)-2-(N-(phenylsulfonyl)amino)-3,3-(ethylenedithio)-1,7-dihydroxyheptane 
• 88425-32-5 (S)-2-(N-(phenylsulfonyl)amino)-3-oxo-1,7-dihydroxyheptane 
• 88425-38-1 (R)-2-(N-(phenylsulfonyl)amino)-1,7-dihydroxyheptane 
• 156386-97-9 (1Z)-α-Ethyl ω-methyl 2-acetamido-2,3-didehydropimelate 
• 156386-98-0 (1E)-α-Ethyl ω-methyl 2-acetamido-2,3-didehydropimelate 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 
• 6026-86-4 methyl 4-formylbutanoate 
• 88425-43-8 (R)-2-(N-(phenylsulfonyl)amino)-1,7-heptanedioic acid 
• 627-76-9 alpha-aminopimelic acid 

Relevant academic research and scientific papers

Peptides of 2-aminopimelic acid: Antibacterial agents that inhibit diaminopimelic acid biosynthesis

Succinyl-CoA:tetrahydrodipicolinate-N-succinyltransferase is a key enzyme in the biosynthesis of diaminopimelic acid (DAP), a component of the cell wall peptidoglycan of nearly all bacteria. This enzyme converts the cyclic precursor tetrahydrodipicolinic

alpha -AMINO ACIDS AS CHIRAL EDUCTS FOR ASYMMETRIC PRODUCTS. A GENERAL SYNTHESIS OF D- alpha -AMINO ACIDS FROM L-SERINE.

A short and chirally efficient synthesis of four D- alpha -amino acids is described with L-serine as the chiral educt. The key C-C bond-forming reactions are the aminoacylations of organometallics with the lithium salt of N-(phenylsulfonyl)-L-serine (2) to give optically pure N-blocked alpha -amino ketones. Reduction of the carbonyl group to carbinol or methylene followed by oxidation of the hydroxymethyl to carboxyl gives the N-blocked D-amino acids. The examples investigated (norleucine, alpha -aminopimelic acid, DOPA, and allothreonine) demonstrate the broad applicability of the method.

D-2-AMINOPIMELIC ACID AND TRANS-3,4-DEHYDRO-D-2-AMINOPIMELIC ACID FROM ASPLENIUM UNILATERALE

D-2-Aminopimelic acid and a novel amino acid, trans-3,4-dehydro-D-2-aminopimelic acid were isolated and characterized from Asplenium unilaterale.Their distribution in Aspleniaceae was also investigated. - Key Word Index: Asplenium unilaterale; Aspleniaceae; (R)-2-aminoheptanedioic acid; (E)-(R)-2-amino-3-heptenedioic acid; D-amino acids; stereochemistry; chemotaxonomy.