322406-96-2

Basic information

• Product Name: 3-cyano-4-(4-cyanophenyl)-5-ethoxycarbonyl-6-methyl1,4-dihydropyridine-2(3H)-thione
• Synonyms: 3-cyano-4-(4-cyanophenyl)-5-ethoxycarbonyl-6-methyl1,4-dihydropyridine-2(3H)-thione
• CAS NO: 322406-96-2
• Molecular Weight: 325.391
• Mol File: 322406-96-2.mol

Chemical Properties

• CAS DataBase Reference: 3-cyano-4-(4-cyanophenyl)-5-ethoxycarbonyl-6-methyl1,4-dihydropyridine-2(3H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyano-4-(4-cyanophenyl)-5-ethoxycarbonyl-6-methyl1,4-dihydropyridine-2(3H)-thione(322406-96-2)
• EPA Substance Registry System: 3-cyano-4-(4-cyanophenyl)-5-ethoxycarbonyl-6-methyl1,4-dihydropyridine-2(3H)-thione(322406-96-2)

Safety Data

• Hazardous Substances Data: 322406-96-2(Hazardous Substances Data)

Downstream Products

• 322406-99-5 2-carbamoylmethylthio-3-cyano-4-(4-cyanophenyl)-5-ethoxycarbonyl-6-methyl-1,4-dihydropyridine 

Relevant articles and documents

Synthesis and properties of 3-cyano-4-(4-cyanophenyl)-1,4-dihydropyridine-2(3H)-thiones

Piperidinium 3-cyano-4-(4-cyanophenyl)-1,4-dihydropyridine-2(3H)-thiolates were obtained by the condensation of 1,3-dicarbonyl compounds, 4-cyanobenzaldehyde, and cyanothiacetamide in the presence of an equimolar amount of piperidine. The acidification of these thiolates gave the corresponding1,4-dihydropyridine-2(3H)-thiones and pyridine-2(1H9-thione. Alkylation of 1,4-dihydropyridine-2-thiolates or the reaction mixture of the three-carbon condensation using iodacetamide gave 2-carbamoylmethylthio-1,4,5,6-tetrahydro- or 1,4-dihydropyridines, which were characterized by their conversion to 4,7-dihydrothieno[2,3-b]pyridines.